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Application Note Modernized Impurity Analysis of the Kinase Inhibitor Imatinib by High-Resolution LC With MS-Compatible Mobile Phases

 

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Application Note Structural Elucidation of Unknown Impurities in the Kinase Inhibitor Imatinib Using UHPLC and High-Resolution Mass Spectrometry Peng Chen, Matthew A. Lauber Waters Corporation Abstract A UHPLC-HRMS method has revealed previously unidentified impurities in the synthesis of the kinase…
Key words
imatinib, imatinibkinase, kinaseelucidation, elucidationinhibitor, inhibitorstructural, structuralimpurities, impuritiesunknown, unknownuhplc, uhplcspectrometry, spectrometryresolution, resolutionmass, masshigh, highusing, usinguplc, uplcchemical
Session F6 A Systematic Approach Towards UPLC® Method Development Esa Lehtorinne [email protected] Tel: +358-9-5659 6288 Fax: +358-9-5659 6282 Waters Finland Kutomotie 16 00380 Helsinki ©2011 Waters Corporation 1 Challenges of Method Development  Chromatographic methods are developed for different applications…
Key words
csh, cshphenyl, phenylselectivity, selectivityuplc, uplcmethanol, methanolacetonitrile, acetonitrilehexyl, hexylfluoro, fluorophase, phasedevelopment, developmentsystematic, systematicdesign, designmobile, mobilemodifier, modifierqbd
UPLC COLUMNS AND CONSUMABLES
2014|Waters|Brochures and specifications
UPLC COLUMNS AND CONSUMABLES UPLC Columns www.waters.com/uplccolumns 109 TABLE OF CONT ENTS Introduction........................................................................................................................................................................ 111 UPLC Columns........................................................................................................................................................................111 Waters UPLC Particle Technology..........................................................................................................................................111 CORTECS UPLC 1.6 µm Columns.................................................................................................................................... 112 CORTECS UPLC C18+ Columns...............................................................................................................................................112 CORTECS UPLC C18 Columns.................................................................................................................................................113 CORTECS UPLC HILIC Columns..............................................................................................................................................113 ACQUITY UPLC…
Key words
uplc, uplcbeh, behphenyl, phenylcsh, cshhilic, hilichss, hsskit, kitacquity, acquitycolumns, columnscortecs, cortecsfluoro, fluorocyano, cyanomethod, methodamide, amidehexyl
Application Note Lipid Nanoparticle Compositional Analysis Using Charged Surface Hybrid Phenyl-Hexyl Separation With Evaporative Light Scattering Detection Bonnie A. Alden, Giorgis Isaac, Weibin Chen, Matthew A. Lauber Waters Corporation Need Help? To learn more about how Waters can help you…
Key words
lipid, lipidhexyl, hexylphenyl, phenylevaporative, evaporativehydrophobicity, hydrophobicitystationary, stationaryscattering, scatteringacquity, acquityhelp, helpnanoparticle, nanoparticlenanoparticles, nanoparticlescsh, cshlight, lightuplc, uplcgarnering
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