ANALYSIS OF OLIGONUCLEOTIDE IMPURITIES ON AN UHPLC-TOF MS SYSTEM WITH A MODIFIED SURFACE TECHNOLOGY

 

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[ APPLICATION NOTEBOOK ] APPLICATION SOLUTIONS FOR OLIGONUCLEOTIDES Table of Contents Introduction – UPLC Analysis of Synthetic Oligonucleotides......................................................................................................................... 4 [ HPLC & UPLC Separations ] Real-Time Analysis of RNAi Duplexes ....................................................................................................................................................................... 8 Semi-Preparative Scale Single-Stranded RNA Purification .......................................................................................................................... 11 Oligonucleotide…
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Rich Motyka, Mot ka Arnie Aistars, Aistars William C H Hudson, dson Da David id Jones Technologies, 25200 Commercentre Drive, Lake Forest, CA 92630, USA Additionally, analytical methods were developed for extracting Propranolol and Metoprolol out of 100 µµL of…
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