ASMS 2021: Application of Vacuum Jacketed UHPLC Columns Coupled with Mass Spectrometry in High Throughput Pharmaceutical AnalysisPosters | 2021 | WatersInstrumentation
Consumables, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC columns
Industries
Pharma & Biopharma
Manufacturer
Waters
Key words

 

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Streamlining Discovery Microsomal Clearance andMetabolite ID Analysis using a TripleTOF® 6600 SystemSWATH® Acquisition 2.0 for Small Molecule ApplicationsMustafa Varoglua*, Lieu Nguyena, Xiaowei Hea**, Keith J. GoodmanbaCubist Pharmaceuticals, Lexington, MA, bSCIEX, Framingham, MA,Present address: *Alnylam Pharmaceuticals, Cambridge, MA, **Eisai Inc, Andover,...
Key words
swath, swathclearance, clearancemetabolite, metabolitequantitative, quantitativeacquisition, acquisitionhigh, highmicrosomal, microsomalproduct, productdiclofenac, diclofenacverapamil, verapamilqualitative, qualitativeion, iondedicated, dedicateddata, dataclint
Ultra-fast LCMS analysis of Antiarrhythmic drugs in plasmaDavide Vecchietti1; Kyoko Watanabe1; Keiko Matsumoto1; Mikael Levi1; Hidetoshi Terada1; Takato Uchikata1; Satoshi Akita11 Shimadzu Corporation., Kyoto, Japan,1. Introduction2.2 Sample preparation3.2 Method evaluation: Gradient elution modeThe need for high throughput liquid chromatography-tandem mass...
Key words
llmi, llmipecision, pecisionulmi, ulmimqc, mqcverapamil, verapamilatenolol, atenololday, daybeneficial, beneficialquantitation, quantitationsotalol, sotaloldrug, drugelution, elutiontens, tensmetoprolol, metoprololpropranolol
Rapid Detection and Quantification of Selected Microsomal Substratesand Metabolites Using the Waters ACQUITY UPLC I-Class Systemand Xevo TQ-S microKerri M. Smith and Paul D. RainvilleWaters Corporation, Milford, MA, USAA P P L I C AT I O N B E...
Key words
dextorphan, dextorphanhydroxydiclofenac, hydroxydiclofenachydroxymephenytoin, hydroxymephenytoinmicrosomal, microsomalsubstrates, substrateshydroxytestosterone, hydroxytestosteronehydroxymidazolam, hydroxymidazolammean, meanhydroxybupropion, hydroxybupropionxevo, xevomicro, microrapid, rapidacetaminophen, acetaminophenaccuracy, accuracymetabolites
Effect of MS Scan Speed on UPLC Peak Separation and MetaboliteIdentification: Time-of-Flight HRMS vs. OrbitrapYun W. Alelyunas, Mark D. Wrona, Kevin Cook, Stephen McDonald, Paul D. RainvilleWaters Corporation, Milford, MA, USAA P P L I C AT I O N...
Key words
glyburide, glyburidemetabolite, metabolitescanning, scanningscan, scanresolution, resolutionmetabolites, metabolitesmicrosomal, microsomalhrms, hrmsincubate, incubateuplc, uplcnegatives, negativesslower, slowerequally, equallyfast, fastspeeds

ASMS 2021: Application of Vacuum Jacketed UHPLC Columns Coupled with Mass Spectrometry in High Throughput Pharmaceutical AnalysisPosters | 2021 | WatersInstrumentation
Consumables, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC columns
Industries
Pharma & Biopharma
Manufacturer
Waters
Key words

 

Similar PDF

Toggle
Streamlining Discovery Microsomal Clearance andMetabolite ID Analysis using a TripleTOF® 6600 SystemSWATH® Acquisition 2.0 for Small Molecule ApplicationsMustafa Varoglua*, Lieu Nguyena, Xiaowei Hea**, Keith J. GoodmanbaCubist Pharmaceuticals, Lexington, MA, bSCIEX, Framingham, MA,Present address: *Alnylam Pharmaceuticals, Cambridge, MA, **Eisai Inc, Andover,...
Key words
swath, swathclearance, clearancemetabolite, metabolitequantitative, quantitativeacquisition, acquisitionhigh, highmicrosomal, microsomalproduct, productdiclofenac, diclofenacverapamil, verapamilqualitative, qualitativeion, iondedicated, dedicateddata, dataclint
Ultra-fast LCMS analysis of Antiarrhythmic drugs in plasmaDavide Vecchietti1; Kyoko Watanabe1; Keiko Matsumoto1; Mikael Levi1; Hidetoshi Terada1; Takato Uchikata1; Satoshi Akita11 Shimadzu Corporation., Kyoto, Japan,1. Introduction2.2 Sample preparation3.2 Method evaluation: Gradient elution modeThe need for high throughput liquid chromatography-tandem mass...
Key words
llmi, llmipecision, pecisionulmi, ulmimqc, mqcverapamil, verapamilatenolol, atenololday, daybeneficial, beneficialquantitation, quantitationsotalol, sotaloldrug, drugelution, elutiontens, tensmetoprolol, metoprololpropranolol
Rapid Detection and Quantification of Selected Microsomal Substratesand Metabolites Using the Waters ACQUITY UPLC I-Class Systemand Xevo TQ-S microKerri M. Smith and Paul D. RainvilleWaters Corporation, Milford, MA, USAA P P L I C AT I O N B E...
Key words
dextorphan, dextorphanhydroxydiclofenac, hydroxydiclofenachydroxymephenytoin, hydroxymephenytoinmicrosomal, microsomalsubstrates, substrateshydroxytestosterone, hydroxytestosteronehydroxymidazolam, hydroxymidazolammean, meanhydroxybupropion, hydroxybupropionxevo, xevomicro, microrapid, rapidacetaminophen, acetaminophenaccuracy, accuracymetabolites
Effect of MS Scan Speed on UPLC Peak Separation and MetaboliteIdentification: Time-of-Flight HRMS vs. OrbitrapYun W. Alelyunas, Mark D. Wrona, Kevin Cook, Stephen McDonald, Paul D. RainvilleWaters Corporation, Milford, MA, USAA P P L I C AT I O N...
Key words
glyburide, glyburidemetabolite, metabolitescanning, scanningscan, scanresolution, resolutionmetabolites, metabolitesmicrosomal, microsomalhrms, hrmsincubate, incubateuplc, uplcnegatives, negativesslower, slowerequally, equallyfast, fastspeeds
 

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