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Application of Vacuum Jacketed UHPLC Columns Coupled with Mass Spectrometry in High Throughput Pharmaceutical Analysis

 

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A P P LICAT ION SOLUT IONS FO R M ETABOLIT E IDENT IFICAT ION A P P L I C AT I O N S O L U T I O N S F O R M E TA…
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Effect of MS Scan Speed on UPLC Peak Separation and Metabolite Identification: Time-of-Flight HRMS vs. Orbitrap Yun W. Alelyunas, Mark D. Wrona, Kevin Cook, Stephen McDonald, Paul D. Rainville Waters Corporation, Milford, MA, USA A P P L I C…
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Streamlining Discovery Microsomal Clearance and Metabolite ID Analysis using a TripleTOF® 6600 System SWATH® Acquisition 2.0 for Small Molecule Applications Mustafa Varoglua*, Lieu Nguyena, Xiaowei Hea**, Keith J. Goodmanb a Cubist Pharmaceuticals, Lexington, MA, bSCIEX, Framingham, MA, Present address: *Alnylam…
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Ultra-fast LCMS analysis of Antiarrhythmic drugs in plasma Davide Vecchietti1; Kyoko Watanabe1; Keiko Matsumoto1; Mikael Levi1; Hidetoshi Terada1; Takato Uchikata1; Satoshi Akita1 1 Shimadzu Corporation., Kyoto, Japan, 1. Introduction 2.2 Sample preparation 3.2 Method evaluation: Gradient elution mode The need…
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