ASMS 2021: Improvements in the bioanalytical method performance for steroid phosphates using a hybrid surface barrier to minimize analyte-metal surface interactions | LabRulez LCMS
 

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A RAPID METHOD FOR THE ULTRA-SENSITIVE QUANTIFICATION OF FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATEFROM HUMAN PLASMAAuthors: Nikunj Tanna, Lauren Mullin & Michael JonesAffiliations: Waters Corporation, Milford, MA, USAINTRODUCTIONMETHODSRESULTSDISCUSSIONFluticasone propionate (Figure 1a) (1) is a synthetictrifluorinated glucocorticoid receptor agonist with antiallergic,anti-inflammatory and...
Key words
fluticasone, fluticasonesalmeterol, salmeterolxinafoate, xinafoatepropionate, propionateaccuracy, accuracyinter, interday, daymqc, mqchqc, hqclqc, lqcplasma, plasmahuman, humanseritide, seritidecone, coneswallowing
Development of a SPE LC-MS/MS Method for the BioanalyticalQuantification of Salmon Calcitonin from Human SerumNikunj Tanna and Mary LameWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■Sensitive and flexible platform forSalmon calcitonin (sCT) is a 32 amino acid (MW 3439.1 Da) syntheticquantification of...
Key words
calcitonin, calcitoninsalmon, salmonquantification, quantificationoasis, oasisspe, spebioanalytical, bioanalyticalserum, serumsct, sctwcx, wcxdevelopment, developmenthuman, humanrecovery, recoveryprotein, proteinprecipitation, precipitationxevo
Application NoteImprovements in Sensitivity for Quantification of SteroidPhosphate Drugs Using ACQUITY PREMIER andMaxPeak HPS ColumnsNikunj Tanna, Robert S. Plumb, Lauren MullinWaters Corporation AbstractAnalytes with electron rich moieties such as phosphate and carboxylate groups are susceptible tochelation with metal surfaces across the...
Key words
hps, hpspremier, premiermaxpeak, maxpeakacquity, acquityphosphate, phosphatehydrocortisone, hydrocortisonedexamethasone, dexamethasonesystem, systemstandard, standardxevo, xevocolumn, columndmso, dmsomore, morechemically, chemicallysurfaces
A Novel Extraction Procedure Using Micro Elution Plates for theEstimation of Docetaxel Using UPLC and ACQUITY TQDP. Veeranjaneyulu, Tirupatewara B. Rao, Sudarshan Mantha, and Dr. Gopal VaidyanathanWaters Corporation, Bangalore, IndiaA P P L I C AT I O N B...
Key words
docetaxel, docetaxeltqd, tqdacquity, acquitymicro, microestimation, estimationelution, elutionplates, plateslloqqc, lloqqcuplc, uplcblank, blankextraction, extractionnovel, novelarea, areamqc, mqclqc
 

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A RAPID METHOD FOR THE ULTRA-SENSITIVE QUANTIFICATION OF FLUTICASONE PROPIONATE AND SALMETEROL XINAFOATEFROM HUMAN PLASMAAuthors: Nikunj Tanna, Lauren Mullin & Michael JonesAffiliations: Waters Corporation, Milford, MA, USAINTRODUCTIONMETHODSRESULTSDISCUSSIONFluticasone propionate (Figure 1a) (1) is a synthetictrifluorinated glucocorticoid receptor agonist with antiallergic,anti-inflammatory and...
Key words
fluticasone, fluticasonesalmeterol, salmeterolxinafoate, xinafoatepropionate, propionateaccuracy, accuracyinter, interday, daymqc, mqchqc, hqclqc, lqcplasma, plasmahuman, humanseritide, seritidecone, coneswallowing
Development of a SPE LC-MS/MS Method for the BioanalyticalQuantification of Salmon Calcitonin from Human SerumNikunj Tanna and Mary LameWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■■■Sensitive and flexible platform forSalmon calcitonin (sCT) is a 32 amino acid (MW 3439.1 Da) syntheticquantification of...
Key words
calcitonin, calcitoninsalmon, salmonquantification, quantificationoasis, oasisspe, spebioanalytical, bioanalyticalserum, serumsct, sctwcx, wcxdevelopment, developmenthuman, humanrecovery, recoveryprotein, proteinprecipitation, precipitationxevo
Application NoteImprovements in Sensitivity for Quantification of SteroidPhosphate Drugs Using ACQUITY PREMIER andMaxPeak HPS ColumnsNikunj Tanna, Robert S. Plumb, Lauren MullinWaters Corporation AbstractAnalytes with electron rich moieties such as phosphate and carboxylate groups are susceptible tochelation with metal surfaces across the...
Key words
hps, hpspremier, premiermaxpeak, maxpeakacquity, acquityphosphate, phosphatehydrocortisone, hydrocortisonedexamethasone, dexamethasonesystem, systemstandard, standardxevo, xevocolumn, columndmso, dmsomore, morechemically, chemicallysurfaces
A Novel Extraction Procedure Using Micro Elution Plates for theEstimation of Docetaxel Using UPLC and ACQUITY TQDP. Veeranjaneyulu, Tirupatewara B. Rao, Sudarshan Mantha, and Dr. Gopal VaidyanathanWaters Corporation, Bangalore, IndiaA P P L I C AT I O N B...
Key words
docetaxel, docetaxeltqd, tqdacquity, acquitymicro, microestimation, estimationelution, elutionplates, plateslloqqc, lloqqcuplc, uplcblank, blankextraction, extractionnovel, novelarea, areamqc, mqclqc
 

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