Overcoming the Challenges of Bispecific Antibody Characterization Using New Column Chemistries to Detect Product Impurities
Posters | 2021 | Agilent Technologies | ASMSInstrumentation
Consumables, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS, LC columns
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsvariants, intact, emicizumab, mab, bispecific, main, subunits, ptms, hic, aggregate, reversed, characterization, chromatography, surmounting, could, eluted, jet, phase, antibody, acidic, biomanufacturing, sheath, stream, temp, nondenaturing, sodium, challenges, gas, charge, biocolumns, basic, dual, impurities, different, finely, monobasic, dibasic, millipore, drawbacks, overcoming, vcap, some, range, peak, asymmetry, flow, iex, aggregates, type, reprint
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counts, countsmab, mabherceptin, herceptinintact, intactpage, pagecontents, contentsbonds, bondsback, backdeglycosylated, deglycosylatedmass, massdeconvoluted, deconvolutedides, idesamu, amubravo, bravoassaymap
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