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Comparability Studies for the Analysis of Nucleotides on Four Different LC Systems

 

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Application Note Pharma & Biopharma HPLC-DAD Analysis of Nucleotides Using a Fully Inert Flowpath Agilent 1260 Infinity II Bio-Inert LC System and a PEEK-lined Agilent InfinityLab Poroshell 120 HILIC-Z Column Authors Koen Sandra, Jonathan Vandenbussche, Gerd Vanhoenacker, Ruben t’Kindt, and…
Key words
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Application Note Biopharma/Pharma Improved Metabolomic Analysis Using an Iron-Free Flow Path Comparing the Agilent 1290 Infinity II Bio LC System and Agilent 1290 Infinity II LC System for metabolomics ×105 ATP 4.5 4.0 Agilent 1290 Infinity II Bio LC Agilent…
Key words
eic, eicatp, atpadp, adpamp, ampcounts, countsmetabolomics, metabolomicstailing, tailingphosphorylated, phosphorylatedgtp, gtpdiphosphate, diphosphatetriphosphate, triphosphateadenylate, adenylatemonophosphate, monophosphatemetabolites, metabolitesadsorption
Keep Your CQA Analysis Biocompatible from Start to Finish PEEK-lined columns and bio-inert supplies to complement the Agilent 1290 Infinity II bio LC system 2 Confidently Measure the Efficacy and Stability of Your Therapeutic Proteins with Agilent Consumables and InfinityLab…
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Technical Overview Demonstrating Inertness for the Analysis of Nucleotides on the Agilent 1290 Infinity II Bio LC ×101 1.7 Adenosine 0.294 1.6 1.5 1.4 AMPcP 1.354 1.3 Response (mAU) 1.2 1.1 1.0 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2…
Key words
ampcp, ampcpadenosine, adenosinenucleotides, nucleotidesadsorption, adsorptioniron, ironinertness, inertnessphosphate, phosphateinteractions, interactionsphosphorylated, phosphorylatedcontaining, containingsystem, systembiocompatible, biocompatiblepeak, peaknonhydrolyzable, nonhydrolyzableinfinity
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