Application Note 20709 SPE-LC-MS/MS Method for the Determination of Nicotine, Cotinine, and Trans-3-hydroxycotinine in Urine

Applications | 2013 | Thermo Fischer ScientificInstrumentation
Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ
Thermo Fischer Scientific
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Kimberly Phipps, Thermo Fisher Scientific, Runcorn, Cheshire, UKKey WordsAccucore C18, dextromethorphan, dextrorphan, SOLA CXAbstractA liquid chromatography–tandem mass spectrometry method for theanalysis of dextromethorphan and dextrorphan from rat plasma has beendeveloped. A limit of quantification of 0.1 ng/mL is readily achieved.When...
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J. Jones, Thermo Fisher Scientific, Runcorn, Cheshire, UKKey WordsSPE, SOLA CX, Syncronis C18, nicotine, cotinine, trans-3-hydroxycotinineAbstractA liquid chromatography tandem mass spectrometry method for nicotine,cotinine, and trans-3-hydroxycotinine in urine has been developed. UsingThermo Scientific™ SOLA™ CX cartridges or plates, sample preparation...
Key words
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APPLICATION NOTENo. 20936SPE and LC-MS/MS method for thedetermination of 25-Hydroxyvitamin D2 and25-Hydroxyvitamin D3 from human plasmaAuthors: Jon Bardsley, Ken Meadows,Joanne Jones, Thermo Fisher Scientific,Runcorn, UKKeywords:Solid phase extraction, SPE, SOLA HRP,LC-MS/MS, Syncronis C18, 25-hydroxyvitaminD2, 25-hydroxyvitamin D3AbstractA liquid chromatography-tandem mass spectrometry method...
Key words
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Joanne Jones, Thermo Fisher Scientific, Runcorn, UKAppli cat i on N ote 2 0 9 3 6SPE and LC-MS/MS Method for theDetermination of 25-Hydroxyvitamin D2and 25-Hydroxyvitamin D3 from HumanPlasmaKey WordsSolid phase extraction, SPE, SOLA HRP, LC-MS/MS, Syncronis C18,25-hydroxyvitamin D2, 25-hydroxyvitamin...
Key words
overspike, overspikeaverage, averageresponse, responsearea, areaqch, qchqcm, qcmqcl, qclvitamin, vitaminfisher, fishergrade, gradescientific, scientificconcentration, concentrationhormone, hormonerecovery, recoverypart