Charge Variant and Aggregation Analysis of Innovator and Biosimilars of Rituximab
Applications | 2019 | Agilent TechnologiesInstrumentation
Consumables, HPLC, LC columns
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordsinnovator, variants, biosimilars, rituximab, rsd, hmws, area, basic, lmws, main, mau, mab, charge, acidic, peak, aggregation, retention, monomer, time, were, biosimilar, min, variant, bio, response, dls, between, hydrodynamic, molecular, radius, similarities, fom, iex, profiles, aggregate, data, analysis, buffer, differences, agilent, correlator, separation, truncation, openlab, used, percent, weight, sourced, explorer, comparison
Similar PDF
Seamless Method Transfer from an Agilent 1260 Infinity Bio-inert LC to an Agilent 1260 Infinity II Bio-inert LC
2016|Agilent Technologies|Applications
Seamless Method Transfer from an Agilent 1260 Infinity Bio-inert LC to an Agilent 1260 Infinity II Bio-inert LC Charge Variant Analysis of Rituximab Innovator and Biosimilar Application Note Biologics & Biosimilars Author Abstract Sonja Schneider Monitoring the charge heterogeneity of…
Key words
biosimilar, biosimilarinnovator, innovatorbio, bioinert, inertrituximab, rituximabcharge, chargevariants, variantsadvisor, advisormau, mauvariant, variantbuffer, buffermin, minsystem, systemlymphoma, lymphomascouting
Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs
2017|Agilent Technologies|Applications
Charge Heterogeneity Analysis of Rituximab Innovator and Biosimilar mAbs Application Note Author Abstract Suresh Babu C.V. This Application Note describes the high-resolution separation of charge variants Agilent Technologies India Pvt. Ltd, of innovator and biosimilar rituximab using an Agilent 1260…
Key words
innovator, innovatorbiosimilar, biosimilarrituximab, rituximabvariant, variantvariants, variantsristova, ristovacharge, chargereditux, redituxmau, maucpb, cpbbasic, basicprofiles, profilesacidic, acidicmabs, mabsmin
Separate and Quantify Rituximab Aggregates and Fragments with High-Resolution SEC
2017|Agilent Technologies|Applications
Separate and Quantify Rituximab Aggregates and Fragments with High-Resolution SEC The Agilent 1260 Infinity Bio-Inert Quaternary LC System and the AdvanceBio SEC 300Å, 2.7 µm Column Application Note Biologics and Biosimilars Author Abstract M.Sundaram Palaniswamy Monoclonal antibody aggregation can arise…
Key words
innovator, innovatoraggregates, aggregatesbiosimilar, biosimilarrituximab, rituximabintact, intactmau, maufragments, fragmentsstressed, stressedsec, secmabs, mabsadvancebio, advancebiostress, stressmonomer, monomerarea, areaaggregation
Agilent 1290 Infinity II 2D-LC solution Biopharmaceutical Polymer Analysis
2017|Agilent Technologies|Presentations
Agilent 1290 Infinity II 2D-LC Solution Biopharmaceutical Polymer Analysis WCBP Jan 2017 Washington, DC 1 Overview • Resolving power and how to measure it • Why two-dimensional LC? • Setup of a 2D-LC System • Different modes of 2D-LC •…
Key words
dimension, dimensionheart, heartwcx, wcxcutting, cuttingcharged, chargedhilic, hiliccharge, chargewax, waxinnovator, innovatorcuts, cutsmultiple, multipleanalysis, analysistiter, titermonoclonal, monoclonalpeak