Your InfinityLab HPLC Productivity Roadmap

Significance of the Topic

Modern analytical laboratories face constant pressure to integrate new instruments quickly and efficiently. Agilent’s CrossLab Productivity Roadmap for InfinityLab HPLC systems provides a structured approach to maximize uptime, ensure data accuracy, and accelerate the return on investment. This roadmap addresses common barriers such as limited staffing, complex site preparation, and lengthy validation processes, helping labs adapt cutting-edge chromatography solutions with minimal disruption.

Study Objectives and Overview

This guide aims to support every phase of a new HPLC instrument implementation. Key objectives include:

• Identifying the optimal InfinityLab HPLC configuration for specific applications.
• Streamlining delivery, installation, and first-run processes.
• Standardizing sample preparation workflows to protect column integrity.
• Optimizing routine operations and maintenance to reduce downtime.
• Maximizing long-term productivity and compliance through service plans and training.

Methodology and Instrumentation

The roadmap is built around a combination of best-practice procedures, digital tools, and expert services:

• Hardware: InfinityLab 1220, 1260, 1290 Infinity II LC systems; preparative and bio-inert variants; SPE and 2D-LC solutions.
• Software: OpenLab CDS, OpenLab ChemStation, MassHunter for data acquisition and reporting.
• Services: CrossLab installation, first-run assist, preventive maintenance, on-site and online training, and compliance consulting.
• Resources: My Order portal for status tracking and site checklists; Agilent Community and Knowledge Portal for troubleshooting and peer support.

Main Findings and Discussion

Implementing this structured approach leads to measurable benefits:

• Reduced setup time and fewer service calls by following defined site preparation and configuration guides.
• Improved method robustness and reproducibility through tailored sample preparation strategies (filtration, SPE, QuEChERS, glycan labeling kits).
• Enhanced operational efficiency via routine preventive maintenance, smart consumable alerts, and method optimization support.
• Lower total cost of ownership by leveraging Agilent Certified Pre-Owned instruments and flexible financial solutions.

Benefits and Practical Applications

By adopting the roadmap, laboratories can:

• Minimize workflow disruptions during instrument installation and validation.
• Ensure compliance with audit requirements using digital qualification and electronic documentation.
• Build in-house expertise through targeted training paths and first-run assistance.
• Extend column life and data quality by applying best-practice sample handling and solvent management.
• Sustain high throughput with remote monitoring, smart alerts, and centralized asset scheduling.

Future Trends and Opportunities

Emerging developments will further enhance lab productivity:

• Integration of predictive maintenance powered by data analytics and IoT sensors.
• Expanded use of cloud-based instrument monitoring and virtual support to reduce onsite visits.
• Increased automation of sample preparation workflows, especially for biopharmaceutical analytics.
• Community-driven method repositories and AI-assisted troubleshooting accelerating problem resolution.

Conclusion

Agilent’s InfinityLab HPLC Productivity Roadmap offers a comprehensive blueprint for laboratories to deploy new chromatography systems with confidence. By combining tailored hardware configurations, robust software tools, expert services, and proactive training, labs can achieve faster time to first result, sustained operational efficiency, and long-term return on investment.

Used Instrumentation

• Agilent InfinityLab 1220, 1260, and 1290 Infinity II LC systems (binary, quaternary, preparative, bio-inert).
• InfinityLab Online SPE and 2D-LC solutions.
• OpenLab CDS, OpenLab ChemStation, MassHunter software platforms.
• AdvanceBio columns and Gly-X N-glycan prep kits.