Expanding Size-Exclusion Chromatography Platform Method Versatility for Monoclonal Antibody Analysis Using Waters XBridge Premier Protein SEC Columns
Applications | 2022 | WatersInstrumentation
Consumables, LC columns, GPC/SEC
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordsxbridge, sec, premier, versatility, expanding, monoclonal, exclusion, protein, antibody, platform, size, waters, columns, chromatography, method, using, analysis, column, mab, bioresolve, beh, mildly, nacl, unspecific, lmw, filtered, bonded, peo, hmw, therapeutic, biosimilar, diol, performance, recombinant, variants, bridgedethylene, buffers, dpbs, organosilica, potentially, high, interactions, employed, condition, hardware, heat, evaluate, capability, terminated, other
Similar PDF
Modern Size-Exclusion Chromatography Separations of Biosimilar Antibodies at Physiological pH and Ionic Strength
2022|Waters|Applications
Application Note Modern Size-Exclusion Chromatography Separations of Biosimilar Antibodies at Physiological pH and Ionic Strength Stephan M. Koza, Hua Yang, Ying Qing Yu Waters Corporation Abstract The state of protein derived self-associated, aggregated, and fragmented impurities in therapeutics are critical…
Key words
biosimilar, biosimilarphysiological, physiologicalmodern, modernstrength, strengthionic, ionicantibodies, antibodiesexclusion, exclusionsec, secseparations, separationssize, sizepremier, premierchromatography, chromatographydpbs, dpbsxbridge, xbridgesuperdx
SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs
2021|Waters|Guides
[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…
Key words
sec, secexclusion, exclusionsize, sizeuplc, uplcacquity, acquitychromatography, chromatographyprotein, proteinaggregates, aggregateshplc, hplcdispersion, dispersioncolumn, columnmonomer, monomerantibody, antibodyigg, igghmws
Rapid SEC-UV Analysis of Monoclonal Antibodies Using Ammonium Acetate Mobile Phases
2023|Waters|Applications
Application Note Rapid SEC-UV Analysis of Monoclonal Antibodies Using Ammonium Acetate Mobile Phases Stephan M. Koza, Albert H. W. Jiang, Ying Qing Yu Waters Corporation Abstract A 4 minute high resolution size-exclusion with UV absorbance detection (SEC-UV) method for the…
Key words
sec, secantibodies, antibodiesmonoclonal, monoclonalammonium, ammoniumphases, phasesacetate, acetaterapid, rapidmobile, mobileanalysis, analysisusing, usingversus, versusvariants, variantscolumn, columnmab, mabbioaccord
Waters ACQUITY and XBridge Premier Protein SEC 250 Å Columns: A New Benchmark in Inert SEC Column Design
2022|Waters|Applications
Application Note Waters ACQUITY and XBridge Premier Protein SEC 250 Å Columns: A New Benchmark in Inert SEC Column Design Lavelay Kizekai, Matthew A. Lauber Waters Corporation Abstract One of the major limitations in protein size-exclusion chromatography (SEC) is the…
Key words
design, designsecondary, secondaryinteractions, interactionsionic, ionichydrophobic, hydrophobichardware, hardwareundesired, undesiredprotein, proteinsurfaces, surfacesxbridge, xbridgemaxpeak, maxpeaksec, secnacl, naclacquity, acquitypremier