ECOM ECP201L PREPARATIVE PUMP

Importance of the Topic

Preparative liquid chromatography requires reliable delivery of solvents at high flow rates and pressures for efficient purification and scale-up. The ECP201L pump addresses these demands by combining robust mechanical design with precise flow control and software integration.

Objectives and Study Overview

This summary outlines the design, performance specifications and operational features of the ECP201L preparative pump. It highlights its pressure and flow capabilities, material compatibility, control interfaces and software support to inform users in analytical and preparative laboratories.

Methodology and Instrumentation

The ECP201L employs two parallel pistons with 20 mm diameter to achieve pressures up to 15 MPa at flow rates up to 1000 ml/min. Key wetted materials include stainless steel, PEEK, Tefzel TM, Kalrez and ceramic. Control options cover RS232, LAN, USB and IO interfaces. Software compatibility includes a free basic version of ECOMAC and full integration with Clarity. Optional features encompass high-pressure gradient operation with up to four units, piston back-washing for buffered solvents and accessory FEP tubing with luer lock fittings.

• Flow range: 2–1000 ml/min
• Maximum pressure: 15 MPa at 1000 ml/min
• Flow accuracy: ±2 %; repeatability: ±1 %
• Wetted materials: stainless steel, PEEK, Tefzel, Kalrez, ceramic
• Control interfaces: RS232, LAN, USB, IO
• Supported OS: Windows XP to Windows 10 (32/64-bit)

Main Results and Discussion

Testing demonstrates stable and precise solvent delivery across the full flow range, with minimal pulsation due to parallel pistons. Gradient formation is consistent when multiple units are synchronized via software control. Piston back-washing significantly extends seal lifetime during buffer‐rich runs. Data export in multiple formats streamlines record keeping and method development.

Benefits and Practical Applications

• High throughput purification in preparative chromatography laboratories
• Scalable gradient operation for method development and scale-up
• Extended seal lifetime with back-washing when using buffer solutions
• Seamless integration with ECOMAC and Clarity software platforms

Future Trends and Potential Applications

• Higher pressure operation for subcritical fluid chromatography applications
• Integration with process analytical technology (PAT) for real-time monitoring
• Development of AI-driven gradient optimization and smart pump control
• Adoption of green solvents requiring advanced seal materials and compatibility

Conclusion

The ECP201L preparative pump offers a versatile and robust solution for high-pressure liquid chromatography needs. Its precise flow control, material compatibility and advanced software support make it ideal for diverse applications in pharmaceutical, chemical and biotech industries. Optional gradient control and back-washing further enhance its performance and longevity.

Reference

ECOM spol. s r.o. ECP201L Preparative Pump Specification Sheet