Analysis of Oligonucleotide Therapeutics using MALDI-8030 and LCMS-9030
Applications | 2022 | ShimadzuInstrumentation
MALDI, LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerShimadzu
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Analysis of Oligonucleotide Therapeutics using MALDI-8030 and LCMS-9030
2022|Shimadzu|Applications
Application News MALDI-TOF Mass Spectrometry Analysis MALDI-8030 Liquid Chromatograph Mass Spectrometer LCMS™-9030 Analysis of Oligonucleotide Therapeutics using MALDI-8030 and LCMS-9030 Y.Yamazaki User Benefits Confident characterization of oligonucleotides Elemental formula confirmation by ESI-QTOF Information of sequence by MALDI-ISD…
Key words
isd, isdesi, esioligonucleotide, oligonucleotidemaldi, maldispectrum, spectrumoligo, oligonews, newsmass, masstherapeutics, therapeuticsdoubtless, doubtlessgenedesign, genedesignqtof, qtofdeconvoluted, deconvolutedデコンボリューションスペクトル, デコンボリューションスペクトルtofms
Oligonucleotide Therapeutics Solution Guide
2022|Shimadzu|Guides
C10G-E097 Oligonucleotide Therapeutics Solution Guide Types and Characteristics of Oligonucleotide Therapeutics Oligonucleotide therapeutics are nucleic acid polymers generally comprised of a few to several dozen bases However, it is a practical problem that oligonucleotide therapeutics are degraded and excreted rapidly…
Key words
excision, excisionunprotected, unprotecteddds, ddscharacteristic, characteristicindex, indexoligomer, oligomerpharmacokinetics, pharmacokineticsquality, qualityoligonucleotide, oligonucleotidecontrol, controlsynthesis, synthesispurification, purificationmodification, modificationtorast, torastanalysis
Qualification and Quantitation of Phosphorothioate Oligonucleotides Using a Quadrupole-Time-of-Flight Mass Spectrometer
2020|Shimadzu|Posters
WP 459 Qualification and Quantitation of Phosphorothioate Oligonucleotides Using a Quadrupole-Time-of-Flight Mass Spectrometer Noriko Kato, Yusuke Inohana, Tairo Ogura, Masaki Yamada, Toshiya Matsubara Shimadzu Corporation. 1, Nishinokyo-Kuwabaracho Nakagyo-ku, Kyoto 604–8511, Japan 3. Methods 1. Overview The purpose of this study…
Key words
mipomersen, mipomersenoligonucleotide, oligonucleotidephosphorothioate, phosphorothioatelna, lnaanalogues, analoguesmonoisotopic, monoisotopicoligonucleotides, oligonucleotidesspectrum, spectrumome, omecharge, chargemass, massdeconvoluted, deconvolutedquantitation, quantitationusing, usingresolution
Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030
2020|Shimadzu|Applications
Application News No. C215 LC-MS Determination of Molecular Mass and Quantification of Oligonucleotide Therapeutics Using Quadrupole Time-of-Flight Mass Spectrometer LCMS™-9030 Overview Oligonucleotide therapeutics are synthetic oligonucleotides that demonstrate their medical efficacy through binding to target genes or target proteins…
Key words
oligonucleotide, oligonucleotidemass, masstherapeutics, therapeuticsshimadzu, shimadzuusing, usingqtof, qtofデコンボリューションスペクトル, デコンボリューションスペクトルcurve, curvequadrupole, quadrupoledeconvolution, deconvolutionデフォルト, デフォルトflow, flownews, newscalibration, calibrationanalysis