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Large Scale Targeted Protein Quantification Using HR/AM Selected Ion Monitoring with MS/MS Confirmation on a Novel Hybrid, Q-OT-qIT Mass Spectrometer

Posters | 2013 | Thermo Fisher Scientific | ASMSInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Proteomics
Manufacturer
Thermo Fisher Scientific
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Large Scale Targeted Protein Quantification Using HR/AM Selected Ion Monitoring with MS/MS Confirmation on the Orbitrap Fusion Tribrid MS R. Kiyonami,1 M. Senko,1 V. Zabrouskov,1 J. Egertson, 2 S. Ting, 2 M. MacCoss, 2 A. FR Hühmer1 Thermo Fisher Scientific,…
Key words
sim, simdia, diaproteins, proteinsfusion, fusionorbitrap, orbitrapdynamic, dynamicsix, sixquantifying, quantifyingbovine, bovinetribrid, tribridorders, orderstargeted, targetedspiked, spikedworkflow, workflowdata
Large Scale Targeted Protein Quantification using HR/AM Selected Ion Monitoring with MS/MS Confirmation on the Orbitrap Fusion Tribrid MS R. Kiyonami1, M. Senko1, V. Zabrouskov1, J. Egertson2, S. Ting2 , M. MacCoss2, A. FR Hühmer1 1Thermo Fisher Scientific, San Jose,…
Key words
dia, diasim, simproteins, proteinsdynamic, dynamicions, ionsquantifying, quantifyingworkflow, workflowcid, cidtargeted, targetedusing, usingorders, orderssix, sixprecursor, precursorwindows, windowsisolation
Reiko Kiyonami, Michael Senko, Vlad Zabrouskov, Andreas F.R. Hühmer, Thermo Fisher Scientific, San Jose, CA, USA Jarrett Egertson, Sonia Ting, Michael MacCoss, University of Washington, Seattle, WA, USA Appli cat i on N ote 6 0 0 Large-Scale Targeted Protein…
Key words
heavyk, heavykwisim, wisimdia, diaheavyr, heavyrsim, simcarboxymethyl, carboxymethylcid, cidorbitrap, orbitrapdata, datapeptide, peptidefusion, fusiontargeted, targetedquantified, quantifiedproteins, proteinsisolation
Targeted Quantitative Proteomics
|Thermo Fisher Scientific|Brochures and specifications
Targeted Quantitative Proteomics Targeted protein quantification with high-resolution, accurate-mass MS Highly selective • Very sensitive • Complex samples HR/AM A more complete quantitative proteomics picture Many of the limitations associated with traditional SRM assays for the verification stage of the…
Key words
targeted, targetedquantification, quantificationdia, diaabundance, abundancepeptide, peptideprm, prmmsxsim, msxsimtargets, targetsrelative, relativeisolation, isolationprotein, proteinsim, simmultiplexed, multiplexedexactive, exactivehigh
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