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Utilizing Empower™ Software to Streamline and Automate the Detection of Sample-to- Sample Differences within Peptide Maps of Biopharmaceuticals

 

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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
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DEPLOYING EFFICIENT WORKFLOWS FOR PEPTIDE MAPPING WITH LC-UV/MS PLATFORMS Kellen DeLaney, Robert E. Birdsall, Ying Qing Yu Waters Corporation, Milford, MA, United States INTRODUCTION Peptide mapping is widely used in biopharmaceutical laboratories across workflows from attribute identification and early-stage process…
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Application Note Method Scaling from ACQUITY™ Premier to Arc™ Premier System Xiangsha Du, Kellen DeLaney, Robert E. Birdsall, Tatyana Friedman Waters Corporation Abstract Instruments capable of delivering consistent and reproducible results are highly desirable for efficient development and manufacturing of…
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Application Note Applying Peptide Mapping and MultiAttribute Method (MAM) Workflow for Biosimilar mAb Drug Products Comparison on the Xevo™ G3 QTof Platform Kellen DeLaney, Samantha Ippoliti, Lisa Reid, Owen Cornwell, Ying Qing Yu, Emma Harry, Mark Towers Waters Corporation Abstract…
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