Agilent MassHunter software suite
Brochures and specifications | 2022 | Agilent TechnologiesInstrumentation
Software is critical to maximize throughput and confidence in mass spectrometry analysis. Agilent MassHunter streamlines instrument control, data acquisition and interpretation to meet demands of modern laboratories.
This article presents the design and features of Agilent’s MassHunter software suite, aiming to simplify workflows across diverse MS applications. It highlights modules for data acquisition, quantitation, qualitative screening, bioanalysis and reporting.
The software supports liquid and gas chromatography coupled with single quad, triple quad and high‐resolution MS.
MassHunter enables automated method setup, autotune optimization and WalkUp batch processing for error‐free operation. Quantitative workflows provide built‐in templates and customizable review for high‐confidence results. Targeted screening via PCDLs simplifies compound identification. BioConfirm facilitates protein and oligonucleotide characterization with deconvolution and sequence confirmation. High‐resolution tools allow accurate mass fragment searching and custom library creation. Non‐target workflows integrate spectral libraries and pattern recognition.
Integration of artificial intelligence for automated data interpretation, cloud‐based collaboration, enhanced multi‐omics workflows and real‐time quality monitoring are poised to extend MassHunter capabilities. Expanded libraries and predictive analytics will drive discovery in environmental, pharmaceutical and clinical research.
Agilent MassHunter streamlines mass spectrometry workflows from acquisition to reporting, delivering accuracy and efficiency across applications. Its modular design and compliance features make it a versatile solution for modern analytical laboratories.
None provided.
Software
IndustriesManufacturerAgilent Technologies
Summary
Importance of the Topic
Software is critical to maximize throughput and confidence in mass spectrometry analysis. Agilent MassHunter streamlines instrument control, data acquisition and interpretation to meet demands of modern laboratories.
Objectives and Study Overview
This article presents the design and features of Agilent’s MassHunter software suite, aiming to simplify workflows across diverse MS applications. It highlights modules for data acquisition, quantitation, qualitative screening, bioanalysis and reporting.
Methodology and Instrumentation
The software supports liquid and gas chromatography coupled with single quad, triple quad and high‐resolution MS.
- LC instruments: Agilent 1290 Infinity II, 6495 TQ, 6230B TOF, 6546 Q‐TOF
- GC instruments: Agilent 8890/5977B, 7250 GC/Q‐TOF
- Software modules: Acquisition, Quantitative, Qualitative, BioConfirm, Mass Profiler Pro, PCDL Manager
Key Results and Discussion
MassHunter enables automated method setup, autotune optimization and WalkUp batch processing for error‐free operation. Quantitative workflows provide built‐in templates and customizable review for high‐confidence results. Targeted screening via PCDLs simplifies compound identification. BioConfirm facilitates protein and oligonucleotide characterization with deconvolution and sequence confirmation. High‐resolution tools allow accurate mass fragment searching and custom library creation. Non‐target workflows integrate spectral libraries and pattern recognition.
Benefits and Practical Applications
- Reduced training and standardized procedures accelerate lab productivity
- Flexible reporting templates minimize bottlenecks in result communication
- Compliance features support regulatory guidelines such as 21 CFR Part 11
- CrossLab services offer instrument qualification, maintenance and compliance outsourcing
Future Trends and Potential Applications
Integration of artificial intelligence for automated data interpretation, cloud‐based collaboration, enhanced multi‐omics workflows and real‐time quality monitoring are poised to extend MassHunter capabilities. Expanded libraries and predictive analytics will drive discovery in environmental, pharmaceutical and clinical research.
Conclusion
Agilent MassHunter streamlines mass spectrometry workflows from acquisition to reporting, delivering accuracy and efficiency across applications. Its modular design and compliance features make it a versatile solution for modern analytical laboratories.
Used Instrumentation
- Agilent 1290 Infinity II HPLC
- Agilent 8890/5977B GC/MSD
- Agilent 6495 TQ LC/MS
- Agilent 6230B TOF LC/MS
- Agilent 6546 LC/Q‐TOF
- Agilent 7250 GC/Q‐TOF
Reference
None provided.
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