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Chromatographic and Mass Spectrometry Approaches to Supporting Biologics Development

 

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Analytical Solutions from Cell Culture to Biologics Development and Quality Control Mridul Mandal; Brian Domanski1; Stephen Kurzyniec1; Stephen Swartz1 1Shimadzu Scientific Instruments, Columbia, MD Overview • • • Biopharmaceuticals such as monoclonal antibodies (mAbs) and antibody drug conjugates (ADCs) have…
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Qualitative Characterization and Quantitative Assessment of Monoclonal Antibodies Using Protein Metrics and nSMOL coupled with the Shimadzu LCMS-9030 QTOF Vikki Johnson, Stephen Kurzyneic Shimadzu Scientific Instruments, Inc., Carlsbad, CA 800-477-1227 1. Introduction In this poster, we use the new LC-MS…
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No. SSI-LCMS-116 Liquid Chromatography Mass Spectrometry No. LCMS-116 N-Linked Glycans Analysis of Monoclonal Antibodies, Biosimilars, and Glycoproteins with High Resolution Mass Spectrometry and Fluorescence Detection using Restek’s Raptor Polar X Column and Protein Metrics’ Software Suite ■ Introduction Therapeutic antibodies…
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C10G-E089 Guide to Biopharmaceutical Solutions —From Cell Line Optimization to Pharmacokinetics— Solutions Designed for Biopharmaceutical Workflows Optimization DNA/RNA Analysis P. 8–9 P. 4–7 Analysis of Metal Elements in Culture Solutions P. 12–13 Colony Picking Analysis of Chemical Components in Culture…
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