LC-MS-based host cell protein (HCP) identification and monitoring during biopharmaceutical downstream process development
Applications | 2021 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordshcp, pool, abundance, hcps, cex, relative, aex, protein, peptide, downstream, mab, phospholipase, process, ppm, host, aiex, cell, vanquish, quantitated, min, poros, identification, time, setting, purification, sgtasvvcllnnfypr, mass, quantitation, thermo, finder, nqvsltclvk, modifications, scientific, proteins, dtlmisr, rpi, maximum, term, risk, value, culture, protease, ciex, width, biopharma, flex, step, measured, threshold, chromatography
Similar PDF
Easy, fast and reproducible analysis of host cell protein (HCP) in monoclonal antibody preparations
2019|Thermo Fisher Scientific|Applications
APPLICATION NOTE 21918 Easy, fast and reproducible analysis of host cell protein (HCP) in monoclonal antibody preparations Authors Giorgio Oliviero1, Ken Cook 2, Kai Scheffler3, Florian Füssl1, Jonathan Bones1 1National Institute for Bioprocessing Research and Training, Dublin, Ireland; 2Thermo Fisher…
Key words
hcp, hcppeptide, peptidemapping, mappinghcps, hcpshost, hostbead, beadsmart, smartkingfisher, kingfishersetting, settinglane, lanecell, celldigest, digestanalysis, analysischarge, chargemab
A Comprehensive Approach for HCP Identification, Quantification, and Monitoring Based on a Single Dimension (1D) LC Separation
2018|Waters|Applications
[ APPLICATION NOTE ] A Comprehensive Approach for HCP Identification, Quantification, and Monitoring Based on a Single Dimension (1D) LC Separation Catalin Doneanu, 1 Sarah Lennon, 2 Malcolm Anderson, 2 Ian Reah, 3 Mal Ross, 3 Steven Anderson, 3 Ian…
Key words
biphosphate, biphosphatealdolase, aldolasefructose, fructosehcp, hcpsonar, sonarhcps, hcpstpqiqvysr, tpqiqvysrtvywdrdm, tvywdrdmmse, msehost, hostnote, noteaddgrpfpqvik, addgrpfpqvikphpypaltpeqk, phpypaltpeqksqvqasytfk, sqvqasytfkapplication
Host Cell Protein Analysis Using Agilent AssayMAP Bravo and 6545XT AdvanceBio LC/Q-TOF
2018|Agilent Technologies|Applications
Application Note Biotherapeutics and Biosimilars Host Cell Protein Analysis Using Agilent AssayMAP Bravo and 6545XT AdvanceBio LC/Q-TOF Authors Linfeng Wu, Shuai Wu and Te-Wei Chu Agilent Technologies, Inc., Santa Clara, CA, USA Introduction Use of biopharmaceuticals such as monoclonal antibodies…
Key words
hprp, hprpiterative, iterativeprotein, proteinfractionation, fractionationassaymap, assaymapbravo, bravocounts, countspeptide, peptideunfractionated, unfractionatedxic, xicdynamic, dynamicwere, werehcps, hcpsusing, usingbyologic
Advancing Host Cell Protein Analyses Through the Combined Use of Microscale 2D RP/RP with CSH C18 and Ion Mobility Enabled MS Detection
2014|Waters|Applications
Advancing Host Cell Protein Analyses Through the Combined Use of Microscale 2D RP/RP with CSH C18 and Ion Mobility Enabled MS Detection Matthew A. Lauber, Catalin E. Doneanu, Stephan M. Koza, Weibin Chen, and Kenneth J. Fountain Waters Corporation, Milford,…
Key words
microscale, microscaleuplc, uplcacquity, acquityplgs, plgsprotein, proteinasm, asmmab, mabhcp, hcpclass, classdigest, digesttvm, tvmprecursor, precursorhost, hosthcps, hcpsuniprot