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Pathway Targeted Metabolomic Analysis in Oral Cancer Cells Using High Performance Ion Chromatography Coupling to a New HR/AM Orbitrap Mass Spectrometry

Posters | 2014 | Thermo Fisher Scientific | ASMSInstrumentation
LC/Orbitrap, IC-MS, IC/MS/MS
Industries
Metabolomics
Manufacturer
Thermo Fisher Scientific
Key words
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Junhua Wang1, Terri Christison1, Krista Backiel2, Grace Ji3, Shen Hu3, Linda Lopez1, Yingying Huang1, Andreas Huhmer1. 1Thermo Fisher Scientific Inc., San Jose, CA; 2Cambridge Isotope Laboratories Inc., Tewksbury, MA; 3 School of Dentistry and Jonsson Comprehensive Cancer Center, UCLA, Los…
Key words
tca, tcacancer, cancertargeted, targetedcells, cellsendogenous, endogenousmetabolites, metabolitesisotope, isotopemetabolomics, metabolomicsnontargeted, nontargetedstable, stablecycle, cyclestandards, standardspyruvate, pyruvatecapic, capicinvasive
Terri Christison1 and Junhua Wang2 Thermo Fisher Scientific, Sunnyvale, CA 2 Thermo Fisher Scientific, San Jose, CA 1 Appli cat i on N ote 1 1 3 7 Untargeted Metabolic Profiling of Oral Cancer Cells Using Capillary Ion Chromatography Coupled…
Key words
capillary, capillarycancer, canceroral, oralmetabolites, metaboliteshram, hramwere, wereneck, neckmetabolite, metaboliteaconitate, aconitateeluent, eluentexactive, exactivemonophosphate, monophosphatemass, massuhplc, uhplccells
CUSTOMER APPLICATION NOTE 73265 Targeted metabolomics method using IC Orbitrap with high resolution mass spectrometry Authors: Yoshihiro Izumi, Takeshi Bamba, Medical Institute of Bioregulation, Kyushu University, Research Center for Transomics Medicine, Division of Metabolomics Keywords: Anionic compound, samplepretreatment, ion chromatography,…
Key words
exactive, exactivemetabolites, metabolitesnegative, negativeion, ionsuppressor, suppressorapproach, approachmeasurement, measurementpotassium, potassiumsystem, systemphosphate, phosphatecamp, campeluent, eluentmass, masspolar, polarwater
separation as the frontend is widely used for expanding coverage in global metabolomics studies. While reversed phase RPLC (C18-based) is the method most widely applied to metabolomics studies, alternatives such as hydrophilic interaction chromatography (HILIC) and mixed-mode chromatography have obtained…
Key words
abundance, abundancemetabolites, metabolitesrplc, rplcrelative, relativegood, goodmin, minhilic, hilicmixed, mixedyellow, yellowtype, typeretention, retentionendogenous, endogenousseparation, separationesi, esigreen
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