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Evaluation of Bench-top Quadrupole Orbitrap Ultra High Resolution MS for Use in Clinical Research in Rapid Quantitative Analysis of Vitamin D in Human Plasma

Posters | 2015 | Thermo Fisher Scientific | MSACLInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Clinical Research
Manufacturer
Thermo Fisher Scientific
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Ap plica t ion Note 63 6 Rapid Analysis of 25-Hydroxyvitamin D3, epi-25-Hydroxyvitamin D3, and 25-Hydroxyvitamin D2 in Plasma for Clinical Research Using High-Resolution Mass Spectrometry Mindy Gao, James Goldberg, Thomas Carrell, and Marta Kozak Thermo Fisher Scientific, San Jose,…
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Mindy Gao, Joe Di Bussolo, Marta Kozak Thermo Fisher Scientific, San Jose, CA Key Words Q Exactive Focus, methylmalonic acid, MMA, clinical research Goal To evaluate the performance of the Thermo Scientific™ Q Exactive™ Focus benchtop quadrupole-Orbitrap mass spectrometer as…
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Methods Calibrators Calibrators containing cyclosporin A, everolimus, sirolimus, and tacrolimus in whole blood were purchased from Chromsystems Instruments & Chemicals GmbH (TABLE 1). Evaluation of Benchtop Quadrupole Orbitrap Ultra-High-Resolution Mass Spectrometer in Rapid Quantitative Analysis of Immunosuppressant Evaluation of Benchtop…
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cyclosporin, cyclosporintacrolimus, tacrolimuseverolimus, everolimussirolimus, sirolimusquantifier, quantifierimmunosuppressant, immunosuppressantrelative, relativeanalyte, analyteabundance, abundanceblood, bloodascomycin, ascomycinpositive, positivequadrupole, quadrupoleclinical, clinicalorbitrap
High-Resolution Accurate-Mass (HRAM) Phthalate Screening using Direct Analysis in Real Time (DART) Ambient Ionization Catharina Crone,1 Markus Kellmann,1 Yue Xuan,1 Elizabeth Crawford2 1 Thermo Fisher Scientific, Bremen, Germany; 2IonSense, Inc., Saugus, MA, USA Overview Purpose: Demonstrating the analysis of phthalic…
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hcd, hcdmass, massdart, dartorder, orderabundance, abundancefragments, fragmentsrelative, relativedirect, directphthalate, phthalatepackaging, packagingstandards, standardsorbitrap, orbitrapscreening, screeningambient, ambientsource
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