810 Sample Processor

Significance of the topic

Automated sample handling is a fundamental component in modern analytical laboratories. The Metrohm 810 Sample Processor addresses the demand for reproducible titrations and unattended sample analysis by combining precise mechanical handling with robust software control.

Objectives and overview

This manual describes the design, setup, and safe operation of the 810 Sample Processor integrated with Metrohm titration instruments. It covers installation, configuration, connectivity, routine maintenance, and troubleshooting to optimize laboratory workflows.

Applied methodology and instrumentation used

• Turntable with configurable racks and magnet coding for sample identification
• Motorized lift and tower with titration head adapter for electrodes, dosing tips, and stirrers
• Integrated membrane pump and external pump interface for rinsing and aspiration
• Connectivity via USB, Metrohm Serial Bus (MSB), and Remote Box for stirrers, dosing devices, and external accessories
• Safety shield, drip pan, and beaker sensor for operator protection and fault detection

Main features and discussion

The 810 Sample Processor offers modular connectivity (USB, MSB, remote TTL) and flexible sample tray options supporting tubes, vials, and beakers up to 42 cm in diameter. Automated electrode rinsing with spray nozzles, precise sample positioning via robotic swing head or direct lift, and integration with Dosino/Dosimat systems ensure standardized titrations. The device’s software interface enables full compliance with regulatory guidelines, such as FDA 21 CFR 11.

Benefits and practical applications

By automating repetitive handling tasks, the system improves throughput and consistency while reducing human error and exposure to hazardous chemicals. It streamlines acid-base titrations, Karl Fischer moisture determinations, and other volumetric analyses in QA/QC, research environments, and production control.

Future trends and possibilities of use

Emerging laboratory information management system (LIMS) interfaces, cloud connectivity, and machine-learning algorithms for predictive maintenance will further enhance the processor’s value. Miniaturized sample racks and integration with microfluidic modules are anticipated to meet the demand for high-throughput nano-scale analyses.

Conclusion

The Metrohm 810 Sample Processor represents a versatile and reliable solution for automated titration workflows, combining robust hardware and flexible software control to improve laboratory efficiency and compliance.

References

No external literature references were provided in the source text.