Chromatography Columns and Supplies Catalog

Importance of High-Quality Chromatography Supplies

Chromatographic analysis underpins modern analytical chemistry across pharmaceutical, environmental, food, and clinical laboratories. Reliable sample preparation, clean mobile phases, robust columns, and precise liquid handling are essential to achieve sensitive, reproducible, and high-throughput measurements. High‐performance consumables minimize matrix interferences and hardware downtime while maximizing instrument uptime and data quality.

Overview of Waters Chromatography Portfolio

Waters Corporation offers an integrated suite of products covering:

• Sample preparation—solid-phase extraction (SPE), QuEChERS kits, protein precipitation, phospholipid removal (Oasis, Ostro, DisQuE).
• Consumables—syringe filters, solvent filtration apparatus, Certified Vials and Containers.
• Liquid chromatography—ultra-to-prep scales of columns (BEH, CSH, HSS, CORTECS, XBridge).
• Automation—Andrew+ robotic pipetting, Pipette+ guided manual pipetting, OneLab software, Otto SPEcialist manifold.

Methodologies and Instrumentation

Sample cleanup workflows include:

• Solid‐phase extraction using polymeric (Oasis HLB/PRiME, MCX, MAX) and silica (Sep-Pak) sorbents with simplified 3- or 4-step protocols to remove proteins, salts, and phospholipids.
• QuEChERS dispersive extraction with DisQuE pouches and cleanup tubes for multi-residue pesticide analysis.
• Pass-through Ostro plates for combined protein precipitation and phospholipid removal.

Liquid handling and automation:

• Andrew+ robot with single- and multichannel pipettes for fully automated protocols.
• Pipette+ stand with bluetooth-enabled electronic pipettes for guided, traceable manual pipetting.
• OneLab software for protocol design, execution, and data management across devices.
• Otto SPEcialist positive-pressure manifold for semi-automated 96-well and cartridge SPE workflows.

Chromatographic hardware:

• Columns spanning 1.6 to 10 µm, including BEH, CSH, HSS hybrid particles and CORTECS solid-core technology for LC, UHPLC, and UPLC.
• MaxPeak Premier high-performance surfaces for mitigating active-site interactions with acidic, basic, and metal-sensitive analytes.
• Certified glass containers (≤15 ppb TOC) for ultra-clean solvent reservoirs.

Main Benefits and Practical Applications

• Cleaner extracts reduce ion suppression in LC-MS and extend column lifetime.
• Standardized, vendor‐certified vials, filters, and containers ensure batch-to-batch consistency.
• Automation solutions increase sample throughput, reduce manual errors, and improve reproducibility.
• Modular SPE and QuEChERS kits simplify method transfer and regulatory compliance.
• Scalable column chemistries enable method transfer from UPLC to prep-scale and vice-versa without reoptimization.

Future Trends and Opportunities

Advances likely include:

• Further integration of AI-driven method development and real-time process analytics.
• Next-generation surfaces for direct analysis of extreme pH or high-salt matrices.
• Broader adoption of micro- and nanoflow LC-MS with ultra-sensitive low-dead-volume hardware.
• Continual improvement in sustainable consumables, including solvent-minimizing SPE and green packaging.

Conclusion

Optimal chromatographic performance relies on harmonized workflows from sample prep to data acquisition. Waters’ broad portfolio of certified consumables, advanced particle-based columns, and automated liquid-handling platforms empowers laboratories to achieve consistent, high-quality results while reducing labor, solvent consumption, and instrument maintenance. Innovations in surface chemistries and integrated automation will further enhance method robustness and meet emerging analytical challenges.

References

1. Waters Sample Preparation Solutions Catalog 2023–2024.
2. Waters Certified Containers Quality Policy.
3. MaxPeak Premier High Performance Surfaces Whitepaper (720007439).
4. Oasis Solid-Phase Extraction Brochure (186007549).
5. OneLab and Andrew Alliance Technical Overview (waters.com/andrewalliance).