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A fast and simple immuno-mass spectrometry method for preclinical bioanalysis for IgG1 mAb

Applications | 2020 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
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Pharma & Biopharma
Manufacturer
Thermo Fisher Scientific
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A Fast and Simple Immuno-mass Spectrometry Based Method Enables Universal Preclinical Bioanalysis for IgG-1 Type mAb Jiashu Tang, Yue Zhou, Thermo Fisher Scientific, No.27 Xin JinQiao Road, Pudong, Shanghai, China. 201206 ABSTRACT RESULTS On-bead digestion and signature peptides determination Purpose:…
Key words
bead, beaddigestion, digestionsignature, signaturediff, diffbeads, beadspeptides, peptidesintra, intraimmuno, immunointer, interstreptavidin, streptavidindigest, digestsmart, smartintegrity, integrityvivo, vivostructure
Antibody Drug Conjugate Bioanalysis using the BioBA Solution A Robust and Accurate Quantification of Ado-Trastuzumab Emtansine Using the BioBA Solution and the SCIEX QTRAP® 6500+ System Michael Deng and Ian Moore SCIEX, Concord, Canada Key Challenges of Antibody-Drug Conjugate Bioanalysis…
Key words
bioba, biobaiyptngytr, iyptngytrsignature, signaturesurfactant, surfactantantibody, antibodydtlmisr, dtlmisremtansine, emtansinepeptide, peptidestd, stdadcs, adcsado, adoheterogeneous, heterogeneousadc, adctrastuzumab, trastuzumabbioanalysis
Rapid quantitation of therapeutic antibodies in animal plasma
2017|Thermo Fisher Scientific|Applications
APPLICATION NOTE 21692 Rapid quantitation of therapeutic antibodies in animal plasma Application benefits Author Xin Zhang , John O’Grady , Kevin Meyer2 1 Thermo Fisher Scientific, Sunnyvale, CA, USA 2 Perfinity Biosciences Inc., West Lafayette, IN, USA • Rapid sample…
Key words
igg, iggdigest, digestsmart, smartdigestion, digestionhuman, humanprotein, proteinkits, kitsanti, antireputable, reputableimmunoaffinity, immunoaffinityimmunocapture, immunocapturebead, beadstreptavidin, streptavidinsupplier, suppliercapture
Rapid quantitation of therapeutic antibodies in animal plasma
2017|Thermo Fisher Scientific|Applications
APPLICATION NOTE 21692 Rapid quantitation of therapeutic antibodies in animal plasma Application benefits Author Xin Zhang , John O’Grady , Kevin Meyer2 1 Thermo Fisher Scientific, Sunnyvale, CA, USA 2 Perfinity Biosciences Inc., West Lafayette, IN, USA • Rapid sample…
Key words
igg, iggdigest, digestsmart, smartdigestion, digestionhuman, humanprotein, proteinkits, kitsanti, antireputable, reputableimmunoaffinity, immunoaffinityimmunocapture, immunocapturebead, beadstreptavidin, streptavidinsupplier, supplierantibodies
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