Highly sensitive and robust LC-HRAM-MS method for simultaneous quantitation of sixteen nitrosamines in multiple drug products
Applications | 2023 | Thermo Fisher ScientificInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordsprm, nipma, nnea, nitroso, nda, ndpha, nitrosamine, nmpa, nmor, metformin, nmba, nmea, npyr, npip, neipa, ndipa, ndma, positive, ndpa, sim, ndba, ndea, impurity, impurities, valsartan, levels, drug, loq, exactive, arb, nitrosamines, tablets, orbitrap, name, ppm, plus, hrms, flex, recovery, api, type, rsd, quaternary, number, uhplc, marketed, vanquish, linearity, genotoxic, nce
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counts, countsintensity, intensitynmba, nmbamin, minnmor, nmornitrosamine, nitrosaminenmpa, nmpaneipa, neipandma, ndmanpip, npipndipa, ndipandpa, ndpandba, ndbandea, ndeaimpurity
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metformin, metforminpositive, positivenmpa, nmpandma, ndmanitrosamine, nitrosaminendba, ndbanmba, nmbanmea, nmeanpyr, npyrnpip, npipneipa, neipandipa, ndipandpa, ndpandea, ndeadrug