A Robust and Sensitive Instrument for Quantification of N-Nitroso Nortriptyline Impurity in Amitriptyline Drug Product
Others | 2023 | WatersInstrumentation
LC/MS, LC/MS/MS, LC/QQQ
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordsnortriptyline, impurity, cronos, radar, nitroso, xevo, ndsris, loq, uplc, acquity, serotonin, increasing, group, class, acquires, drug, spiked, demo, quantification, tertiary, scan, nitrosamine, amitriptyline, thought, recovery, avoided, interact, tablets, nitrite, overcome, called, india, instrument, formed, substance, amino, challenges, plus, needs, form, impurities, effect, lab, mrm, contamination, presence, related, method, robust, improve
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propranolol, propranololcronos, cronosradar, radarnitroso, nitrosohydrochloride, hydrochloridexevo, xevondsri, ndsriadrenergic, adrenergicloq, loqcomplications, complicationsacquires, acquiresdrug, drugdemo, demoquantification, quantificationovercomes
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labetalol, labetalolcronos, cronosradar, radarimpurity, impuritynitroso, nitrosoxevo, xevopursue, pursueloq, loquplc, uplcacquity, acquityacquires, acquiresspiked, spikeddemo, demoquantification, quantificationscan
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