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Novel tandem nano and capillary flow LC-MS-based approach for facile 24/7 proteome profiling with near 100% MS utilization

Posters | 2023 | Thermo Fisher Scientific | HPLC SymposiumInstrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Industries
Proteomics
Manufacturer
Thermo Fisher Scientific
Key words
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LC-MS TECHNICAL NOTE Vanquish Neo UHPLC system sets new performance standards for single-shot nanoLCMS bottom-up proteomics Authors biomarker discovery and precision medicine. The enormous variety and dynamic range of proteins found in biofluids such Runsheng Zheng , Christopher Pynn ,…
Key words
neo, neonanolcms, nanolcmsvanquish, vanquishpepmap, pepmapwash, washcolumn, columnproteomics, proteomicssystem, systemuhplc, uhplcloading, loadingshot, shotouter, outerrates, ratesspray, spraybottom
Double Barrel ESI Source and Novel Tandem NanoLC-MS Setup Enables 24/7 Proteome Profiling with Close to 100% MS Utilization Runsheng Zheng1, Thomas Lanzinner2, Georg Völkle3, Christopher Pynn1, Jan Linnemann2, John Modrow2, Wim Decrop1, Andreas Tebbe2, Peter Jehle1, Mauro De Pra1,…
Key words
nanolc, nanolcwashing, washingtandem, tandemgradient, gradientloading, loadingplatform, platformdeep, deepnano, nanohram, hramequilibration, equilibrationprofiling, profilingproteome, proteomecolumns, columnstwosteps, twostepscolumn
Maximize productivity in proteome profiling
2020|Thermo Fisher Scientific|Technical notes
TECHNICAL NOTE 73671 Maximize productivity in proteome profiling Combining intelligent tandem nanoLC-MS methods and a novel double-barrel ESI source for 100% MS utilization Authors: Runsheng Zheng1, Christopher Pynn1, Thomas Lanzinner2, Georg Völkle3, Jan Linnemann2, John Modrow2, Andreas Tebbe2, Wim Decrop1,…
Key words
nanolc, nanolcnanoviper, nanoviperscientific, scientificthermo, thermowashing, washingtandem, tandeminter, interloading, loadingpump, pumpemitter, emitterpulled, pulledcolumn, columnpacked, packedcolumns, columnssetup
LC-MS Fast, sensitive, and reproducible nano- and capillary-flow LCMS methods for high− throughput proteome profiling using the Vanquish Neo UHPLC system hyphenated with the Orbitrap Exploris 480 MS Authors Introduction Runsheng Zheng , Tabiwang N Arrey , Amirmansoor Hakimi ,…
Key words
neo, neowash, washpepmap, pepmapduration, durationvanquish, vanquishmin, mintrap, trapthroughput, throughputmethods, methodsuhplc, uhplccolumn, columnmethod, methodouter, outerphase, phaseseparation
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