Simultaneous analysis of polysorbate 80 and poloxamer 188 in biopharmaceutical formulations using charged aerosol detector and single quadrupole mass spectrometer
Posters | 2023 | Thermo Fisher Scientific | HPLC SymposiumInstrumentation
HPLC, LC/MS, LC/SQ
IndustriesPharma & Biopharma
ManufacturerThermo Fisher Scientific
Key wordspoloxamer, poe, oleate, sorbitan, romiplostim, isosorbide, protein, concentration, cad, surfactants, isq, formulations, polysorbates, polysorbate, rsd, excipients, recombinant, validation, products, dilutio, method, theoreti, middle, optimizing, isqtm, amount, acclaimtm, thermo, pharmaceutics, indicate, range, suited, european, fit, efficacious, mobile, degradation, wash, single, trademarks, needle, degrading, stabilizing, nonlinear, tetra, stability, peak, detected, quantification, results
Similar PDF
Polysorbate 80 profiling by HPLC with mass and charged aerosol detection
2021|Thermo Fisher Scientific|Applications
APPLICATION NOTE 73979 Polysorbate 80 profiling by HPLC with mass and charged aerosol detection Authors: Mauro De Pra, Denis A. Ispan, Katherine Lovejoy, Sylvia Grosse, Stephan Meding, Frank Steiner Thermo Fisher Scientific, Germering, Germany Keywords: Vanquish Flex, Vanquish Duo, ISQ…
Key words
poe, poeoleate, oleatesorbitan, sorbitanisosorbide, isosorbidecounts, countsinverse, inversegroups, groupscad, cadgradient, gradientisq, isqvanquish, vanquishscientific, scientificminutes, minutespolysorbate, polysorbatemass
Combining mass spectra, retention time modelling, and charged aerosol detection for unambiguous peak annotation and uniform-response quantitation in polysorbate profiling
2022|Thermo Fisher Scientific|Posters
Combining mass spectra, retention time modelling, and charged aerosol detection for unambiguous peak annotation and uniform-response quantitation in polysorbate profiling Denis A. Ispan1, Sara Carillo2, Jonathan Bones2, Ken Cook3, Frank Steiner1, Mauro De Pra1 1Thermo Fisher Scientific, Germering, Germany 2…
Key words
poen, poensorbitan, sorbitanoleate, oleateisosorbide, isosorbidedioleate, dioleatecad, cadannotation, annotationtetraesters, tetraesterstetraoleate, tetraoleateoxyethylene, oxyethylenetrioleate, trioleatemonoester, monoestermixing, mixingmonoesters, monoesterslipase
Novel applications of multi-detector HPLC systems in pharmaceutical analysis
2023|Thermo Fisher Scientific|Posters
Novel applications of multi-detector HPLC systems in pharmaceutical analysis KS Lovejoya, DA Ispana, X Yub, P Pinedo-Gonzalezc, M De Praa, C Liuc, D Howerc, D Luc, S Hackbuschd, S Grossea, S Medinga, F Steiner a, A Lambe, J Bardsleye, M…
Key words
poen, poencad, cadsorbitan, sorbitanoleate, oleateinverse, inverseunknown, unknownleachables, leachablesisosorbide, isosorbideextractables, extractablesgradient, gradientisq, isqpolysorbate, polysorbatenormalization, normalizationquantitation, quantitationcompensation
Separation and Analysis of Polysorbate 80 in the Presence of Human Serum Immunoglobulin G Using Agilent Bond Elut Lipid Extraction SPE Cartridges
2020|Agilent Technologies|Applications
Application Note Biopharma Separation and Analysis of Polysorbate 80 in the Presence of Human Serum Immunoglobulin G Using Agilent Bond Elut Lipid Extraction SPE Cartridges Authors Sanjeewa N. Senadheera, Limian Zhao, and Derick Lucas Agilent Technologies, Inc. Abstract Protein aggregation…
Key words
polysorbate, polysorbatelipid, lipidelut, elutdad, dadbond, bondelsd, elsdpolysorbates, polysorbatesextraction, extractionsurfactant, surfactantwere, werepolynomial, polynomialagilent, agilentmobile, mobilephase, phasecartridges