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Determining mRNA Capping with HILIC-MS on a Low-Adsorption Flow Path

 

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Application Note Biopharma Rapid Analysis of mRNA 5' Capping with High Resolution LC/MS Author Brian Liau Agilent Technologies, Inc. Introduction Industrial-scale production of mRNA has received growing attention due to the ongoing SARS-CoV-2 pandemic. mRNA vaccines have proven to be…
Key words
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Optimizing Oligonucleotide Analysis Oligonucleotide therapeutics are small synthetic nucleic acids that can be used to treat different types of diseases. They act by modulating either gene expression or protein function by binding specific genetic sequences or target proteins.1,2 Due to…
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End-To-End Workflow Solutions for Short Nucleic Acids and mRNA Analysis
2024|Agilent Technologies|Brochures and specifications
Oligo Workflow Resource Guide End-To-End Workflow Solutions for Short Nucleic Acids and mRNA Analysis From R&D to QC/production Short synthetic oligonucleotides, such as small interfering RNA, antisense oligonucleotides, aptamers, and CRISPR guides have gained much attention and grown rapidly as…
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Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…
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