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Confident intact mass analysis of the tRNA isodecoders of phenylalanine by UHPLC-HRAM-MS and BioPharma Finder software

 

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Application note | 001183 Biopharma Characterization of in vitro-transcribed (IVT) mRNA poly(A) tail by LC-HRAM-MS and BioPharma Finder 5.0 software Authors Application benefits Robert L. Ross1, Jenny England2, Rhonda • Confident identification and sequence confirmation of polyadenylated tails in synthetic…
Key words
poly, polytail, tailfinder, finderbiopharma, biopharmapolyadenylated, polyadenylatedmass, massdeconvolution, deconvolutionrelative, relativemrna, mrnaabundance, abundancethermo, thermomonoisotopic, monoisotopicintact, intactdeconvoluted, deconvolutedonec
Application note | 001398 Biopharma Streamlining characterization and monitoring of oligonucleotide impurities using an Orbitrap-based LC-HRAM-MS platform Application benefits Authors Hao Yang , Keeley Murphy , Yi Zhang , 1 2 3 • Comprehensive characterization of oligonucleotides and their impurities…
Key words
oligonucleotide, oligonucleotideflp, flporbitrap, orbitrapexploris, explorisimpurities, impuritiesrna, rnaimpurity, impuritymass, massvanquish, vanquisheworkflow, eworkflowfull, fullchromeleon, chromeleonsequence, sequencecharacterization, characterizationrelative
APPLICATION NOTE 73870 Identification and quantitation of oligonucleotides, impurities, and degradation products Haichuan Liu1, Kevin Guo2, Jennifer Sutton1, Keeley Murphy1, Min Du2 1 Thermo Fisher Scientific, San Jose, CA 2 Thermo Fisher Scientific, Boston, MA Keywords: Oligonucleotide, RNA, impurity, purification,…
Key words
oligonucleotide, oligonucleotideimpurities, impuritiesfinder, finderbiopharma, biopharmaabundance, abundancedesalting, desaltingrelative, relativeagc, agcvalue, valuehplc, hplcsoftware, softwarednapac, dnapaccustom, customintensity, intensitymicroscans
Application note | 001108 Biopharma Characterization of mRNA 5’ capping products using an LC-HRAM-MS/MS analytical platform and Thermo Scientific BioPharma Finder software solution Authors Goal Robert L Ross, Keeley Murphy, Yi Zhang, To develop a sensitive and robust LC-HRAM-MS/MS method…
Key words
decapped, decappedcapped, cappedrnase, rnasedigestion, digestionabundance, abundancerelative, relativethermo, thermomrna, mrnascientific, scientificscan, scandependent, dependentonec, onecbiopharma, biopharmadata, datafinder
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