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Tumor heterogeneity of glioblastoma analyzed via SpatialOMx and HiPLEX-IHC MALDI Imaging

 

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ASMS 2023 MALDI HiPLEX-IHC Imaging of FFPE Human Kidney Tissue at 5 µm utilizing microGRID on timsTOF fleX MALDI-2 Connor West1, Joshua Fischer1, Corrina Henkel2, Sumankalai Ramachandran1, Azad Eshghi1, Gargey Yagnik3, Mark Lim3 1Bruker Scientific LLC, Billerica, MA 01821, USA…
Key words
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timsTOF MALDI Guided SpatialOMx Innovation with Integrity TIMS-MALDI MS MALDI Guided SpatialOMx The tumor microenvironment is a highly variable ecosystem, giving it an intrinsic temporal character. De-coding the cellular communication within the tumor microenvironment via label-free MALDI Imaging and x-omics…
Key words
maldi, maldispatialomx, spatialomxtimstof, timstofflex, fleximaging, imagingbruker, brukerlaunches, launchestumor, tumorscils, scilspasef, pasefmicroenvironment, microenvironmenttissue, tissueomics, omicslab, labtims
MALDI Guided SpatialOMx uncovers proteomic profiles in tumor subpopulations of breast cancer MALDI Guided SpatialOMx provides an excellent possibility to discover deep proteomics insights into heterogeneous tumor subpopulations by retaining the regiospecific information of an imaging technique. Abstract The timsTOF…
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tumor, tumorsubpopulations, subpopulationsmaldi, malditimstof, timstofimaging, imagingsubpopulation, subpopulationsegmentation, segmentationflex, flexlmd, lmdpasef, pasefbreast, breastproteomics, proteomicsspatialomx, spatialomxboundary, boundarywere
ASMS 2023 13 MALDI Imaging of C6-Glucose Uptake Measured in TCA Metabolites from Glioblastoma Mouse Brain Joshua L. Fischer1, Kari Wilder-Romans2, Ethan Yang1, Savannah R. Snyder1, Katherine A. Stumpo1, Angelica Lin2, Zitong Zhao2, Jie Xu2, Daniel R. Wahl2 1 Bruker…
Key words
dosed, dosedglioblastoma, glioblastomascils, scilsflux, fluxhealthy, healthycancerdosed, cancerdosedluta, lutamaldi, maldiimaging, imagingpdx, pdxtca, tcatissue, tissuecancerous, canceroussegmentation, segmentationcancer
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