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IMPROVING SPATIAL DISTRIBUTION, SENSITIVITY AND SELECTIVITY IN MSI, USING A NOVEL DESI QQQ AND A HR-MULTI REFLECTING TOF SYSTEMS

Posters | 2023 | Waters | ASMSInstrumentation
MS Imaging, LC/HRMS, LC/MS, LC/MS/MS, LC/QQQ, LC/TOF
Industries
Clinical Research
Manufacturer
Waters
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NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…
Key words
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MULTI-STEP WORKFLOW FOR VISUALIZATION OF DRUG/METABOLITES AND METABOLISM WITH DESI TQ AND DESI Q-TOF MASS SPECTROMETERS Emmanuelle Claude1; Naysha Munjoma1; Alex Birsan3, Ian Wilson2, Joanne Ballantyne1 1 Waters Corporation, Wilmslow; 2Division of Systems Medicine, Department of Metabolism Department of Metabolism,…
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desi, desiimaging, imagingmsi, msigefitinib, gefitinibdmpk, dmpkwere, weremrm, mrmspectrometers, spectrometersmetabolites, metabolitesputative, putativestudies, studiestissues, tissuestargeted, targetedperformed, performedusing
IMPROVED SELECTIVITY AND ACQUISITION SPEED USING DESI QUADRUPOLE BASED MASS SPECTROMETER 1 Emmanuelle Claude, 1Wei Rao, 2Zoltan Takats, 1Emrys Jones 1 Waters Corporation, Wilmslow, UK; 2Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK INTRODUCTION…
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desi, desiimaging, imagingxevo, xevoterfenadine, terfenadinemrm, mrmenkephalin, enkephalinsprayer, sprayerion, ionexperiment, experimentbeen, beencarboxyterfenadine, carboxyterfenadinedesmethylerlotinib, desmethylerlotinibdidesmethylerlotinib, didesmethylerlotinibhydroxyolanzapine, hydroxyolanzapineleucine
Improved molecular detection and acquisition speed using DESI mass spectrometry imaging quadrupole based mass spectrometer Emmanuelle Claude1, Wei Rao1, Zoltan Takats2, Emrys Jones1 1 Waters Corporation, Stamford Rd, Wilmslow, SK9 4AX, UK; 2 Department of Metabolism, Digestion and Reproduction, Imperial…
Key words
desi, desiimaging, imagingxevo, xevomass, massmetabolites, metabolitesmrm, mrmdesitm, desitmspectrometers, spectrometersspecificity, specificityusing, usingerlotinib, erlotinibterfenadine, terfenadineimaged, imageddrugs, drugsolanzapine
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