Rapid High Sensitivity LC-MS/MS Bioanalytical Method for the Simultaneous Quantification of Gefitinib Based PROTACs – 3 and Gefitinib in Rat Plasma to Support Discovery DMPK Studies
Applications | 2024 | WatersInstrumentation
LC/MS, LC/MS/MS, LC/QQQ
IndustriesPharma & Biopharma
ManufacturerWaters
Key wordsgefitinib, bioanalytical, simultaneous, rapid, quantification, protacs, sensitivity, based, method, high, proteasome, mediated, vivo, molecules, rat, metabolism, chimeras, mobilizing, drug, mouse, previous, degradation, ubiquitin, spectrometry, studies, dmpk, truview, proteolysis, moiety, class, protein, have, neck, small, targeting, absorbed, target, conditions, ionisation, mass, careers, targetlynx, privacy, cookie, cookies, share, preferences, weights, candidate, new
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