Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF | LabRulez LCMS_EN
 

Similar PDF

Toggle
Optimizing Adeno-Associated Virus (AAV) Capsid Protein AnalysisUsing UPLC and UPLC-MSXimo Zhang, Stephan Koza, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAn optimized LC-MS solution for theRecombinant adeno-associated viruses (rAAVs) are the most widelyseparation and intact mass analysisused...
Key words
capsid, capsidaav, aavadeno, adenouplc, uplcvirus, virusassociated, associatedproteins, proteinsoptimizing, optimizingraav, raavtherapy, therapymass, massflr, flrgene, geneacquity, acquityviral
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsmeasure, measureiex, iexrplc, rplcfull, fullsec, secmonitoring
Application NoteLC/MS of Intact Adeno-AssociatedVirus Capsid Proteins for RapidConfirmation of Product IdentityAuthorBrian LiauAgilent Technologies, Inc.IntroductionAdeno-associated viruses (AAVs) are a promising new class of biotherapeuticcapable of treating a host of rare and intractable genetic diseases such as spinalmuscular atrophy and inherited...
Key words
deconvoluted, deconvolutedamu, amucapsid, capsidaav, aavmass, massadeno, adenorresponse, rresponsecounts, countsvirus, virusacquisition, acquisitionfld, fldassociated, associatedprotein, proteintime, timemin
Poster ReprintASMS 2020ThP 466Purity and IdentityCharacterization of AdenoAssociated Virus CapsidParticles by Intact and BottomUp Based LiquidChromatography-MassSpectrometry MethodsWendi A. Hale1, Dominique Garceau2,Tristan Cano2, Caitlin Jaeger2, RoyHegedus2, William Hermans2, NormanGarceau2, Christopher M. Colangelo11Agilent,Lexington, MA2LakePharma,Worcester, MA IntroductionAdeno-associated viruses (AAVs) are the main viralvectors for...
Key words
capsid, capsidviral, viralspectrum, spectrumaavs, aavsswarm, swarmcqas, cqastherapy, therapyintact, intactptms, ptmsgene, geneautotune, autotunepeptide, peptideproteins, proteinstranslational, translationaladvancebiolc
 

Similar PDF

Toggle
Optimizing Adeno-Associated Virus (AAV) Capsid Protein AnalysisUsing UPLC and UPLC-MSXimo Zhang, Stephan Koza, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAn optimized LC-MS solution for theRecombinant adeno-associated viruses (rAAVs) are the most widelyseparation and intact mass analysisused...
Key words
capsid, capsidaav, aavadeno, adenouplc, uplcvirus, virusassociated, associatedproteins, proteinsoptimizing, optimizingraav, raavtherapy, therapymass, massflr, flrgene, geneacquity, acquityviral
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1 Ralph Waldo Emersonb. 1803 - d.1882©2020...
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapyproteins, proteinsmeasure, measureiex, iexrplc, rplcfull, fullsec, secmonitoring
Application NoteLC/MS of Intact Adeno-AssociatedVirus Capsid Proteins for RapidConfirmation of Product IdentityAuthorBrian LiauAgilent Technologies, Inc.IntroductionAdeno-associated viruses (AAVs) are a promising new class of biotherapeuticcapable of treating a host of rare and intractable genetic diseases such as spinalmuscular atrophy and inherited...
Key words
deconvoluted, deconvolutedamu, amucapsid, capsidaav, aavmass, massadeno, adenorresponse, rresponsecounts, countsvirus, virusacquisition, acquisitionfld, fldassociated, associatedprotein, proteintime, timemin
Poster ReprintASMS 2020ThP 466Purity and IdentityCharacterization of AdenoAssociated Virus CapsidParticles by Intact and BottomUp Based LiquidChromatography-MassSpectrometry MethodsWendi A. Hale1, Dominique Garceau2,Tristan Cano2, Caitlin Jaeger2, RoyHegedus2, William Hermans2, NormanGarceau2, Christopher M. Colangelo11Agilent,Lexington, MA2LakePharma,Worcester, MA IntroductionAdeno-associated viruses (AAVs) are the main viralvectors for...
Key words
capsid, capsidviral, viralspectrum, spectrumaavs, aavsswarm, swarmcqas, cqastherapy, therapyintact, intactptms, ptmsgene, geneautotune, autotunepeptide, peptideproteins, proteinstranslational, translationaladvancebiolc
 

Related content

Overcoming the challenges of liquid chromatography method transfer: A CDMO perspective

Technical notes
| 2022 | Thermo Fischer Scientific
Instrumentation
HPLC
Manufacturer
Thermo Fischer Scientific
Industries
---

Method for the determination of 431 Residual Pesticides in Honey using LCMS-8050 and GCMS-TQ8040 NX

Applications
| 2022 | Shimadzu
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

ASMS: IMPROVEMENTS IN SENSITIVITY, QUANTITATIVE LINEARITY, AND ROBUSTNESS USING A MODIFIED BENCH-TOP QUADRUPOLE ORTHOGONAL TIME-OF-FLIGHT MASS SPECTROMETER (Q-TOF MS)

Posters
| 2022 | Waters
Instrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Manufacturer
Waters
Industries
---

Determination of Per and Polyfluoroalkyl Substances in Soils Using Carbon S SPE by LC/MS/MS

Applications
| 2022 | Agilent Technologies
Instrumentation
Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Environmental

ASTM D4327-03 Compliant Analysis of Anions in Wastewater

Applications
| 2022 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Environmental
 

Related content

Overcoming the challenges of liquid chromatography method transfer: A CDMO perspective

Technical notes
| 2022 | Thermo Fischer Scientific
Instrumentation
HPLC
Manufacturer
Thermo Fischer Scientific
Industries
---

Method for the determination of 431 Residual Pesticides in Honey using LCMS-8050 and GCMS-TQ8040 NX

Applications
| 2022 | Shimadzu
Instrumentation
GC/MSD, GC/MS/MS, GC/QQQ, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Shimadzu
Industries
Food & Agriculture

ASMS: IMPROVEMENTS IN SENSITIVITY, QUANTITATIVE LINEARITY, AND ROBUSTNESS USING A MODIFIED BENCH-TOP QUADRUPOLE ORTHOGONAL TIME-OF-FLIGHT MASS SPECTROMETER (Q-TOF MS)

Posters
| 2022 | Waters
Instrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
Manufacturer
Waters
Industries
---

Determination of Per and Polyfluoroalkyl Substances in Soils Using Carbon S SPE by LC/MS/MS

Applications
| 2022 | Agilent Technologies
Instrumentation
Sample Preparation, Consumables, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Agilent Technologies
Industries
Environmental

ASTM D4327-03 Compliant Analysis of Anions in Wastewater

Applications
| 2022 | Shimadzu
Instrumentation
Ion chromatography
Manufacturer
Shimadzu
Industries
Environmental
Other projects
Follow us
More information
WebinarsAbout usContact usTerms of use

LabRulez s.r.o., all rights reserved.