Characterization of Viral Vector Particles Using the Agilent 6545XT AdvanceBio LC/Q-TOF
Applications | 2020 | Agilent TechnologiesInstrumentation
LC/TOF, LC/HRMS, LC/MS, LC/MS/MS
IndustriesPharma & Biopharma
ManufacturerAgilent Technologies
Key wordscapsid, counts, gene, mass, viral, charge, peptide, deconvoluted, adeno, vector, advancebio, cqas, iterative, proteins, therapy, ptms, aavs, tof, amu, aav, feature, virus, unmodified, retinal, sheath, vital, raw, gas, acetylation, agilent, associated, oxidation, swarm, from, mapping, tics, parameter, runs, vcap, temperature, workflow, molecule, confirm, deamidation, flow, data, value, autotune, acquisition, characterization
Similar PDF
Purity and Identity Characterization of Adeno-Associated Virus Capsid Particles by Intact and Bottom-Up Based Liquid Chromatography-Mass Spectrometry Methods
2020|Agilent Technologies|Posters
Poster Reprint ASMS 2020 ThP 466 Purity and Identity Characterization of AdenoAssociated Virus Capsid Particles by Intact and BottomUp Based Liquid Chromatography-Mass Spectrometry Methods Wendi A. Hale1, Dominique Garceau2, Tristan Cano2, Caitlin Jaeger2, Roy Hegedus2, William Hermans2, Norman Garceau2, Christopher…
Key words
capsid, capsidviral, viralspectrum, spectrumaavs, aavsswarm, swarmcqas, cqasintact, intacttherapy, therapyptms, ptmsgene, genepeptide, peptideproteins, proteinsautotune, autotunetranslational, translationaladvancebiolc
LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity
2021|Agilent Technologies|Applications
Application Note LC/MS of Intact Adeno-Associated Virus Capsid Proteins for Rapid Confirmation of Product Identity Author Brian Liau Agilent Technologies, Inc. Introduction Adeno-associated viruses (AAVs) are a promising new class of biotherapeutic capable of treating a host of rare and…
Key words
amu, amudeconvoluted, deconvolutedcapsid, capsidaav, aavmass, massrresponse, rresponseadeno, adenocounts, countsvirus, virusacquisition, acquisitionfld, fldassociated, associatedprotein, proteintime, timemin
Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software
2022|Agilent Technologies|Applications
Application Note Biopharma/Pharma Adeno-Associated Virus Characterization with Agilent 6545XT AdvanceBio LC/Q-TOF and Protein Metrics Byos Software Authors Wendi A. Hale and Christopher M. Colangelo Agilent Technologies Inc. Lexington, MA, USA Michelle English Protein Metrics Cupertino, CA, USA Abstract This application…
Key words
byos, byosprotein, proteinvariant, variantpeptide, peptideiterative, iterativeaavs, aavsreconstruction, reconstructionaav, aavsva, svaxle, xlemetrics, metricsmapping, mappingintact, intactamino, aminosequence
Developing the analytics and analytical workflows supporting the analysis of the next generation of biotherapeutic and gene therapies
2020|Waters|Presentations
Developing the analytics and analytical workflows supporting the analysis of the next generation of biotherapeutic and gene therapies. Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D. Waters Lunch Seminar Tuesday January 28, 2020 WCBP 2020 Diamond Program Partner ©2020 Waters…
Key words
capsid, capsidaav, aavempty, emptydevelopment, developmentgene, geneprotein, proteincapsids, capsidstherapy, therapysec, secfull, fullmonitoring, monitoringproteins, proteinsmeasure, measureiex, iexcharacterization