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Compliant attribute monitoring for biopharmaceutical product quality attributes employing intact mass analysis

 

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A New Level of Compliant-Ready Intact Biotherapeutic Protein Quantification using Reconstructed Masses SCIEX OS Software 1.7 with SCIEX TripleTOF® 6600 System or X500B QTOF System Kerstin Pohl1, Yihan Li2, Ji Jiang2, Xu Guo3, Vanaja Raguvaran3, Lei Xiong2 1 SCIEX Framingham,…
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[ APPLICATION NOTEBOOK ] Multi-Attribute Methods for Biopharmaceutical Analysis Application Notes [ APPLICATION NOTEBOOK ] Introduction The adoption of LC-MS-based multi-attribute method (MAM) analysis for routine monitoring of biotherapeutic variation has progressed greatly over the last five years. The ability…
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Time Course Study of Oxidation Stress Using SCIEX Solution for MAM with the X500B QTOF System Zoe Zhang2, Ji Jiang2, Sean McCarthy1 1 SCIEX Framingham, MA (USA), 2SCIEX Redwood City, CA USA During the development of a biopharmaceutical it is…
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mam, mamattribute, attributebiopharmaceutical, biopharmaceuticaldeclustering, declusteringida, idasciex, sciexaccessible, accessibleprotein, proteinparameter, parameterpotential, potentialoxidation, oxidationtwinspray, twinsprayvalue, valueiondrive, iondrivephase
For Research Use Only. Not for Use In Diagnostic Procedures. Drug Discovery and Development Evaluation of Critical Attributes on Different Lots of Adalimumab Using BPV Flex Software 1.0.1 SCIEX X500B QTOF system Zoe Zhang1, Sean McCarthy2` 2 SCIEX Redwood City,…
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bpv, bpvattributes, attributestrack, trackprocessing, processinggraph, graphflexible, flexibleflex, flexadalimumab, adalimumabmas, masdifferent, differentglycoform, glycoformreconstructed, reconstructedprovides, provideslots, lotsdata
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