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Automated High-Throughput Oligo QC: From Automated Sample Preparation to MALDI Spectra Assessment

 

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Rapid Oligonucleotides QC with Automated High Resolution ESI-LCMS and BioPharma Compass Oligonucleotides – sequences of nucleotides (RNA and DNA) – are vital research tools that have a wide range of applications in genetic testing, research, and forensics. Abstract Common applications…
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Automated High-Throughput Clone Screening of Therapeutic Antibodies: From Automated IdeS Digestion to Intact Fc/2-Glycosylation Analysis by MALDI-TOF The glycosylation status of the Fc/2 region is a critical quality attribute (CQA) of therapeutic antibodies and is typically tested in early stages…
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Bruker Product Overview - Life Science Mass Spectrometry
2020|Bruker|Brochures and specifications
Product Overview Life Science Mass Spectrometry Innovation with Integrity Mass Spectrometry Empowering Science with Innovation and Integrity As one of the world’s leading analytical instrumentation companies, Bruker offers a broad spectrum of advanced solutions in all fields of research and…
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Extensive LC-Top-Down MS Sequence Confirmation of the NISTmAb Reference Material 8671 Characterization of therapeutic antibodies aims on primary sequence validation, localization of modifications such as glycan profiles and the determination of disulfide bond status of the target molecule. Introduction Typically,…
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