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APPLICATION NOTE 64977Sensitive, robust quantitative analysis of amixture of drug candidates in plasma using aTSQ Altis triple quadrupole mass spectrometerAuthorsKeeley Murphy, Simon Szwandt,and Claudia MartinsThermo Fisher Scientific,San Jose, CAKeywordsAntidepressants, LC-MS/MS,TSQ Altis MS, pharmaceutical,small molecules, bioanalysis,bioequivalenceGoalTo develop a sensitive, robust, reproducible...
Key words
altis, altisdesomorphine, desomorphinepositive, positiveflecainide, flecainidedesmethyldoxepin, desmethyldoxepintsq, tsqfluoxetine, fluoxetinemidazolam, midazolamimipramine, imipramineamitriptyline, amitriptylinecrashed, crasheddiazepam, diazepamreproducibility, reproducibilityplasma, plasmadrug
Which LC-MS/MS Platform is Most Appropriate for the Quantitative Analysis of Steroids in Serum for Clinical Research?WP129Rory M Doyle, Douglas McDowell, Thermo Fisher Scientific, 265 Davidson Avenue, Somerset, NJ, USA 08873ABSTRACTPurpose: Steroids control metabolism, inflammation, immune functions, salt and water...
Key words
tsq, tsqpositive, positivealtis, altissteroids, steroidsdhea, dheapregnenolone, pregnenolonecorticosterone, corticosteronequantis, quantiscortisone, cortisoneandrostenedione, androstenedionecortisol, cortisolprogesterone, progesteroneserum, serumfortis, fortisloq
Analysis of Estrone and Estradiol to Low pg/mL Levels in Human Serum by Triple Quadrupole MassSpectrometry for Clinical Research Kristine Van Natta, Neloni Wijeratne, Claudia Martins, Thermo Fisher Scientific, San Jose, CAABSTRACTRESULTSPurpose: For detailed studies, scientists need to quantitate ever...
Key words
estrone, estroneestradiol, estradiolcdc, cdcarb, arbinternal, internalhost, hostlot, lotcalculated, calculatedevaluated, evaluatedeffects, effectsmatrix, matrixarea, areaspiked, spikedstandard, standardpeak
TECHNICAL NOTE 73140Achieving high sensitivity and robustness – analysis of estroneand estradiol in human serum by TSQ Altis mass spectrometerfor clinical researchAuthorsApplication benefitsKristine Van Natta, Neloni Wijeratne,Claudia Martins• Quantitate estrone and estradiol to 2 pg/mL in human plasmaThermo Fisher Scientific,San...
Key words
estrone, estronecdc, cdcestradiol, estradiolhost, hostnegative, negativealtis, altistsq, tsqarb, arbten, tenvanquish, vanquishcalculated, calculatedlot, lotquantitation, quantitationinternal, internalevaluated
 

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APPLICATION NOTE 64977Sensitive, robust quantitative analysis of amixture of drug candidates in plasma using aTSQ Altis triple quadrupole mass spectrometerAuthorsKeeley Murphy, Simon Szwandt,and Claudia MartinsThermo Fisher Scientific,San Jose, CAKeywordsAntidepressants, LC-MS/MS,TSQ Altis MS, pharmaceutical,small molecules, bioanalysis,bioequivalenceGoalTo develop a sensitive, robust, reproducible...
Key words
altis, altisdesomorphine, desomorphinepositive, positiveflecainide, flecainidedesmethyldoxepin, desmethyldoxepintsq, tsqfluoxetine, fluoxetinemidazolam, midazolamimipramine, imipramineamitriptyline, amitriptylinecrashed, crasheddiazepam, diazepamreproducibility, reproducibilityplasma, plasmadrug
Which LC-MS/MS Platform is Most Appropriate for the Quantitative Analysis of Steroids in Serum for Clinical Research?WP129Rory M Doyle, Douglas McDowell, Thermo Fisher Scientific, 265 Davidson Avenue, Somerset, NJ, USA 08873ABSTRACTPurpose: Steroids control metabolism, inflammation, immune functions, salt and water...
Key words
tsq, tsqpositive, positivealtis, altissteroids, steroidsdhea, dheapregnenolone, pregnenolonecorticosterone, corticosteronequantis, quantiscortisone, cortisoneandrostenedione, androstenedionecortisol, cortisolprogesterone, progesteroneserum, serumfortis, fortisloq
Analysis of Estrone and Estradiol to Low pg/mL Levels in Human Serum by Triple Quadrupole MassSpectrometry for Clinical Research Kristine Van Natta, Neloni Wijeratne, Claudia Martins, Thermo Fisher Scientific, San Jose, CAABSTRACTRESULTSPurpose: For detailed studies, scientists need to quantitate ever...
Key words
estrone, estroneestradiol, estradiolcdc, cdcarb, arbinternal, internalhost, hostlot, lotcalculated, calculatedevaluated, evaluatedeffects, effectsmatrix, matrixarea, areaspiked, spikedstandard, standardpeak
TECHNICAL NOTE 73140Achieving high sensitivity and robustness – analysis of estroneand estradiol in human serum by TSQ Altis mass spectrometerfor clinical researchAuthorsApplication benefitsKristine Van Natta, Neloni Wijeratne,Claudia Martins• Quantitate estrone and estradiol to 2 pg/mL in human plasmaThermo Fisher Scientific,San...
Key words
estrone, estronecdc, cdcestradiol, estradiolhost, hostnegative, negativealtis, altistsq, tsqarb, arbten, tenvanquish, vanquishcalculated, calculatedlot, lotquantitation, quantitationinternal, internalevaluated
 

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