Anion-Exchange Chromatography for Determining Empty and Full Capsid Contents in Adeno-Associated VirusApplications | 2020 | WatersInstrumentationHPLCIndustriesClinical ResearchManufacturerWatersKey wordsempty, capsid, capsids, aav, aex, full, virus, adeno, serotypes, anion, associated, minutes, determining, exchange, res, contents, pak, tris, chromatography, recombinant, method, transduction, application, note, separation, protein, microscopy, viral, salt, flr, between, been, development, bis, uplc, acquity, resolution, dutifully, propane, separating, were, bio, rff, starting, buffer, has, purities, particles, particle, may
Determination of Full, Partial and Empty Capsid Ratios for Adeno-Associated Virus (AAV) Analysis
Determination of Full, Partial and Empty Capsid Ratios forAdeno-Associated Virus (AAV) AnalysisTingting Li, Tie Gao, Hongxu Chen, Zuzana Demianova, Fang Wang, Mukesh Malik, Jane Luo, HandyYowanto, Sahana MollahSCIEX, Brea, CAIntroductionAdeno-associated virus (AAV) is one of the most commonlyused delivery vehicles...
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Size-Exclusion Chromatography Analysis of Adeno-Associated Virus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Column and Fluorescence Detection
Size-Exclusion Chromatography Analysis of Adeno-AssociatedVirus (AAV) Preparations Using a 450 Å Diol-Bonded BEH Columnand Fluorescence DetectionStephan M. Koza and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■Optimization of SEC based separationsAs the development of gene therapy products accelerates, the needfor several...
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Optimizing Adeno-Associated Virus (AAV) Capsid Protein Analysis Using UPLC and UPLC-MS
Optimizing Adeno-Associated Virus (AAV) Capsid Protein AnalysisUsing UPLC and UPLC-MSXimo Zhang, Stephan Koza, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAn optimized LC-MS solution for theRecombinant adeno-associated viruses (rAAVs) are the most widelyseparation and intact mass analysisused...
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Developing the analytics and analytical workflows supporting the analysis of the next generation of biotherapeutic and gene therapies
Developing the analytics and analytical workflows supporting the analysisof the next generation of biotherapeutic and gene therapies.Scott J. Berger, Ph.D. and Ximo Zhang, Ph.D.Waters Lunch SeminarTuesday January 28, 2020WCBP 2020DiamondProgram Partner©2020 Waters Corporation. COMPANY CONFIDENTIAL1Ralph Waldo Emersonb. 1803 - d.1882©2020...
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