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[ TECHNOLOGY BRIEF ]Evaluating BioAccord LC-MS System Performance for Deployment of aCompact, SmartMS-Enabled Biopharma Solution in Late Stage Developmentand QC Environment – Intact Mass AnalysisHenry Shion, Jonathan Pugh, Jill Lord, Yun Alelyunas, Ying Qing Yu and Weibin Chen. Waters Corporation,...
Key words
bioaccord, bioaccordsystem, systeminter, interglycoforms, glycoformsintact, intactfive, fiveintra, intrareproducibility, reproducibilitymajor, majormass, massrsd, rsdstudy, studysystems, systemsbrief, briefabundance
[ TECHNOLOGY BRIEF ]Routine Peptide Mapping Analysis using the BioAccord SystemNilini Ranbaduge, Henry Shion, and Ying Qing YuWaters Corporation, Milford, MA, USASmartMS-enabled BioAccord System improves theoperational efficiency for routine peptide mapping analysis.GOALDemonstrate how the BioAccord™ Systemsimplifies routine peptide mapping analysiswith...
Key words
bioaccord, bioaccordpeptide, peptidepurposefully, purposefullymapping, mappingsystem, systemaccessibility, accessibilityprotein, proteininformatics, informaticssmartms, smartmsintegrated, integratedbrief, briefflr, flrtuv, tuvacquity, acquityunifi
[ TECHNOLOGY BRIEF ]Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometryon the BioAccord SystemHenry Shion, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USADrug-to-Antibody Ratio (DAR) determination of Lys andCys conjugated ADCs was accomplished using analyticalscale size...
Key words
bioaccord, bioaccordconjugated, conjugatedadc, adcdar, daradcs, adcsnative, nativedrug, drugsystem, systemantibody, antibodycovalent, covalentbrief, briefsec, secconjugates, conjugatescysteine, cysteinelysine
Application NoteApplication of a Mass Confirmation Workflowfor Biotherapeutics ScreeningHenry Shion, Scott J. Berger, Ying Qing YuWaters Corporation AbstractIn the study, we report the development of a higher throughput intact mass confirmation workflowusing the BioAccord LC-MS System1-10 operated under the control of...
Key words
native, nativeconfirmation, confirmationmass, massreversed, reversedintact, intactacquity, acquityantibody, antibodyrda, rdathroughput, throughputstatus, statussec, secphase, phasenoncovalent, noncovalentuplc, uplcworkflow
 

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[ TECHNOLOGY BRIEF ]Evaluating BioAccord LC-MS System Performance for Deployment of aCompact, SmartMS-Enabled Biopharma Solution in Late Stage Developmentand QC Environment – Intact Mass AnalysisHenry Shion, Jonathan Pugh, Jill Lord, Yun Alelyunas, Ying Qing Yu and Weibin Chen. Waters Corporation,...
Key words
bioaccord, bioaccordsystem, systeminter, interglycoforms, glycoformsintact, intactfive, fiveintra, intrareproducibility, reproducibilitymajor, majormass, massrsd, rsdstudy, studysystems, systemsbrief, briefabundance
[ TECHNOLOGY BRIEF ]Routine Peptide Mapping Analysis using the BioAccord SystemNilini Ranbaduge, Henry Shion, and Ying Qing YuWaters Corporation, Milford, MA, USASmartMS-enabled BioAccord System improves theoperational efficiency for routine peptide mapping analysis.GOALDemonstrate how the BioAccord™ Systemsimplifies routine peptide mapping analysiswith...
Key words
bioaccord, bioaccordpeptide, peptidepurposefully, purposefullymapping, mappingsystem, systemaccessibility, accessibilityprotein, proteininformatics, informaticssmartms, smartmsintegrated, integratedbrief, briefflr, flrtuv, tuvacquity, acquityunifi
[ TECHNOLOGY BRIEF ]Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometryon the BioAccord SystemHenry Shion, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USADrug-to-Antibody Ratio (DAR) determination of Lys andCys conjugated ADCs was accomplished using analyticalscale size...
Key words
bioaccord, bioaccordconjugated, conjugatedadc, adcdar, daradcs, adcsnative, nativedrug, drugsystem, systemantibody, antibodycovalent, covalentbrief, briefsec, secconjugates, conjugatescysteine, cysteinelysine
Application NoteApplication of a Mass Confirmation Workflowfor Biotherapeutics ScreeningHenry Shion, Scott J. Berger, Ying Qing YuWaters Corporation AbstractIn the study, we report the development of a higher throughput intact mass confirmation workflowusing the BioAccord LC-MS System1-10 operated under the control of...
Key words
native, nativeconfirmation, confirmationmass, massreversed, reversedintact, intactacquity, acquityantibody, antibodyrda, rdathroughput, throughputstatus, statussec, secphase, phasenoncovalent, noncovalentuplc, uplcworkflow
 

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