Evaluating BioAccord System Performance in Late Stage Development and QC Environment – Peptide Mapping AnalysisTechnical notes | 2020 | WatersInstrumentationLC/TOF, LC/HRMS, LC/MSIndustriesPharma & BiopharmaManufacturerWatersKey wordsbioaccord, peptide, mapping, system, inter, intra, late, assays, brief, acquity, mass, abundance, waters, digest, retention, intact, systems, developing, within, stage, regulated, concerted, relative, peptides, technology, analysis, reproducible, deviation, plus, spectrometry, uplc, complementing, based, protein, rda, nistmab, performance, skilled, fluctuation, launch, class, flr, use, deployment, biologics, study, tuv, retrospective, standard, plotting
Evaluating BioAccord LC-MS System Performance for Deployment of a Compact, SmartMS-Enabled Biopharma Solution in Late Stage Development and QC Environment – Intact Mass Analysis
[ TECHNOLOGY BRIEF ]Evaluating BioAccord LC-MS System Performance for Deployment of aCompact, SmartMS-Enabled Biopharma Solution in Late Stage Developmentand QC Environment – Intact Mass AnalysisHenry Shion, Jonathan Pugh, Jill Lord, Yun Alelyunas, Ying Qing Yu and Weibin Chen. Waters Corporation,...
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Routine Peptide Mapping Analysis using the BioAccord System
[ TECHNOLOGY BRIEF ]Routine Peptide Mapping Analysis using the BioAccord SystemNilini Ranbaduge, Henry Shion, and Ying Qing YuWaters Corporation, Milford, MA, USASmartMS-enabled BioAccord System improves theoperational efficiency for routine peptide mapping analysis.GOALDemonstrate how the BioAccord™ Systemsimplifies routine peptide mapping analysiswith...
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Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometry on the BioAccord System
[ TECHNOLOGY BRIEF ]Analysis of Antibody Drug Conjugates (ADCs) by Native Mass Spectrometryon the BioAccord SystemHenry Shion, Ying Qing Yu, and Weibin ChenWaters Corporation, Milford, MA, USADrug-to-Antibody Ratio (DAR) determination of Lys andCys conjugated ADCs was accomplished using analyticalscale size...
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Application of a Mass Confirmation Workflow for Biotherapeutics Screening
Application NoteApplication of a Mass Confirmation Workflowfor Biotherapeutics ScreeningHenry Shion, Scott J. Berger, Ying Qing YuWaters CorporationAbstractIn the study, we report the development of a higher throughput intact mass confirmation workflowusing the BioAccord LC-MS System1-10 operated under the control of...
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