Method Development Tools for More Efficient Screening of Biopharmaceutical Method Conditions Using the ACQUITY Arc Bio SystemPart 2 of 2: Screening SEC and IEX Conditions in a Single Experiment | LabRulez LCMS
 

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Auto•Blend Plus Technology for Ion-Exchange ChromatographyMethod Development and Robustness TestingHua Yang, Bill Warren, and Stephan KozaWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAuto•Blend™ Plus TechnologyIon-exchange chromatography (IEX) is widely used for the charge-variantfacilitated IEX method developmentanalysis of protein biotherapeutics. Its ability to...
Key words
blend, blendauto, autoplus, plussalt, saltmethod, methodvariant, variantrobustness, robustnesstechnology, technologyinitial, initialcharge, chargegradient, gradientexchange, exchangedevelopment, developmentminutes, minutestesting
ACQUITY UPLC H-Class Bio SystemBuilt for your biomolecular characterizationt he BIocoM PAt IBle u P lc P lAt FoRMThe ACQUITY UPLC® H-Class Bio System – the latest extension to the familyof ACQUITY UPLC Systems, brings the benefits of UPLCt Technology...
Key words
uplc, uplcbio, bioacquity, acquityclass, classsystem, systemblend, blendauto, autominutes, minutesflexibilit, flexibilitplus, pluscharacterization, characterizationmanager, managerprotein, proteinexchange, exchangeheaters
Application NoteMethod Transfer of Size-Exclusion and IonExchange Methods for MonoclonalAntibody Analysis from HPLC to the ArcPremier SystemBrooke M. Koshel, David Dao, Robert E. Birdsall, Ying Qing YuWaters Corporation AbstractTransferring methods between internal laboratories and external contract organizations is a key part...
Key words
arc, arciex, iexpremier, premierchemistries, chemistriesplatforms, platformshplc, hplcequivalency, equivalencymethods, methodsrepeatable, repeatablesec, sectraditional, traditionalsystem, systemtransferring, transferringsimilar, similardemonstrating
[ APPLICATION NOTEBOOK ]SIZE-EXCLUSIONCHROMATOGRAPHY (SEC)OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ]IntroductionGel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtrationchromatography (GFC) are commonly used terms to describe a liquid chromatographic techniquethat separates compounds based on their relative different...
Key words
sec, secexclusion, exclusionsize, sizeuplc, uplcacquity, acquitychromatography, chromatographyprotein, proteinaggregates, aggregateshplc, hplcdispersion, dispersionmonomer, monomerantibody, antibodyigg, iggcolumn, columnbio
 

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Auto•Blend Plus Technology for Ion-Exchange ChromatographyMethod Development and Robustness TestingHua Yang, Bill Warren, and Stephan KozaWaters Corporation, Milford, MA, USAAPPLICATION BENEFITS■■INTRODUCTIONAuto•Blend™ Plus TechnologyIon-exchange chromatography (IEX) is widely used for the charge-variantfacilitated IEX method developmentanalysis of protein biotherapeutics. Its ability to...
Key words
blend, blendauto, autoplus, plussalt, saltmethod, methodvariant, variantrobustness, robustnesstechnology, technologyinitial, initialcharge, chargegradient, gradientexchange, exchangedevelopment, developmentminutes, minutestesting
ACQUITY UPLC H-Class Bio SystemBuilt for your biomolecular characterizationt he BIocoM PAt IBle u P lc P lAt FoRMThe ACQUITY UPLC® H-Class Bio System – the latest extension to the familyof ACQUITY UPLC Systems, brings the benefits of UPLCt Technology...
Key words
uplc, uplcbio, bioacquity, acquityclass, classsystem, systemblend, blendauto, autominutes, minutesflexibilit, flexibilitplus, pluscharacterization, characterizationmanager, managerprotein, proteinexchange, exchangeheaters
Application NoteMethod Transfer of Size-Exclusion and IonExchange Methods for MonoclonalAntibody Analysis from HPLC to the ArcPremier SystemBrooke M. Koshel, David Dao, Robert E. Birdsall, Ying Qing YuWaters Corporation AbstractTransferring methods between internal laboratories and external contract organizations is a key part...
Key words
arc, arciex, iexpremier, premierchemistries, chemistriesplatforms, platformshplc, hplcequivalency, equivalencymethods, methodsrepeatable, repeatablesec, sectraditional, traditionalsystem, systemtransferring, transferringsimilar, similardemonstrating
[ APPLICATION NOTEBOOK ]SIZE-EXCLUSIONCHROMATOGRAPHY (SEC)OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ]IntroductionGel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtrationchromatography (GFC) are commonly used terms to describe a liquid chromatographic techniquethat separates compounds based on their relative different...
Key words
sec, secexclusion, exclusionsize, sizeuplc, uplcacquity, acquitychromatography, chromatographyprotein, proteinaggregates, aggregateshplc, hplcdispersion, dispersionmonomer, monomerantibody, antibodyigg, iggcolumn, columnbio
 

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