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Improve Sensitivity for Quantification of Antisense Oligonucleotides in Plasma Using Microflow LC MRM Methodology

 

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Extending the Lower Limits of Quantification of a Therapeutic Oligonucleotide Through Microflow LC-MS/MS Featuring SCIEX QTRAP® 6500+ LC-MS/MS System with OptiFlow™ Turbo V source and the SCIEX M5 MicroLC System Daniel Warren, Sean McCarthy, Lei Xiong SCIEX, Framingham, MA, USA…
Key words
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Ultra-Sensitive Quantification of Trastuzumab Emtansine in Mouse Plasma using Trap-Elute MicroLC MS Method Featuring SCIEX QTRAP® 6500+ System with OptiFlow™ Turbo V source and M5 MicroLC system Lei Xiong, Ji Jiang, and Remco van Soest SCIEX, Redwood City, California, USA…
Key words
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Universal Solution for Monoclonal Antibody Quantification in Biological Fluids Using Trap-Elute MicroLC-MS Method Featuring the SCIEX QTRAP® 6500+ LC-MS/MS System with OptiFlow™ Turbo V source and M5 MicroLC system Lei Xiong, Ji Jiang, and Remco van Soest SCIEX, Redwood City,…
Key words
microflow, microflowimmunoaffinity, immunoaffinitymicrolc, microlcphase, phaseflow, flowmobile, mobileelectrode, electrodevalue, valuesample, samplerate, ratetrap, trapuniversal, universalparameter, parameterloading, loadingquantitation
Sub-Picogram Level Quantitation of Desmopressin in Small Volumes of Human Plasma Using a Trap-Elute Microflow Using the QTRAP® 6500+ System with OptiFlow™ Turbo V Source and M5 MicroLC System Rahul Baghla, Khatereh Motamedchaboki, Remco van Soest and Lei Xiong SCIEX,…
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