Agilent InfinityLab Supplies for the Agilent 1290 Infinity II LC with Vialsampler

Significance of the topic

High-performance liquid chromatography (HPLC) is a cornerstone technique in analytical laboratories across pharmaceuticals, environmental monitoring, food safety, and chemical research. Reliable performance and reproducible results depend not only on the instrument itself but also on the quality and compatibility of consumables, spare parts, and maintenance kits. Using genuine, application-matched supplies ensures optimal flow stability, minimal contamination, and extended instrument lifetime.

Objectives and overview

This quick reference guide compiles the most commonly ordered supplies and parts for the Agilent 1290 Infinity II LC system with Vialsampler. It is designed to help analysts and laboratory managers quickly identify the components needed for preventive maintenance, routine operation, and method optimization, thereby reducing downtime and ensuring consistent data quality.

Methodology and used instrumentation

The guide is organized by system modules and consumable types. Key instrumentation and supply categories include:

• Pump Supplies: tubing kits, filters, seals, frits, peristaltic pump components for general, high-speed, and quaternary pumps.
• Detector Supplies: deuterium lamps, flow cells (standard, micro, semi-micro, high-pressure) with repair kits for Variable Wavelength Detector (VWD) and Diode Array Detector (DAD).
• Vialsampler Consumables: vial drawers, needles and seats, rotor seals, sample loops, and metering seals for precise injection.
• Multicolumn Thermostat Components: rotor seals for switching valves, heat exchanger cartridges, column clamps.
• Capillaries and Fittings: capillary tubing of various inner diameters and lengths, Quick-Connect fittings, and Specialty connectors for low-dispersion flow paths.
• Accessory Kits: convenience kits, capillary kits, inline filter kits, system tool kits, solvent bottles with safety caps and identification rings.

Main results and discussion

By standardizing on these Agilent-qualified parts, laboratories can streamline preventive maintenance procedures, minimize the risk of leaks and pressure instability, and reduce blank carryover. The structured categorization of supplies allows quick identification of part numbers and maintenance requirements (e.g., number of components per PM event), leading to faster reordering and reduced system downtime.

Benefits and practical applications

The use of genuine Agilent InfinityLab supplies offers:

• Enhanced reproducibility: consistent flow dynamics and minimized dead volume preserve chromatographic resolution.
• Extended instrument lifetime: precision-manufactured seals, frits, and rotor components reduce wear.
• Regulatory compliance: traceability of parts and materials under ISO 9001 quality systems supports audit readiness.
• Operational efficiency: preassembled convenience and maintenance kits cut preparation time.

Future trends and opportunities

As HPLC applications evolve toward higher throughput and smaller-volume separations, future supply trends will focus on ultra-low-dispersion capillaries, improved micro- and nano-flow consumables, and smart consumables with RFID tracking for automated maintenance logging. Integration with cloud-based service platforms for predictive maintenance and dynamic inventory management will further enhance uptime and cost control.

Conclusion

This reference guide simplifies the selection and procurement of critical supplies for the Agilent 1290 Infinity II LC with Vialsampler. By adopting these genuine components and preventive maintenance kits, laboratories can achieve consistent performance, reduce downtime, and maintain high data quality across diverse analytical applications.

Reference

• Agilent Technologies. Quick Reference Guide for Agilent InfinityLab Supplies for Agilent 1290 Infinity II LC with Vialsampler. October 2018.