AdvanceBio HIC: a Hydrophobic HPLC Column for Monoclonal Antibody (mAb) Variant Analysis
Applications | 2019 | Agilent TechnologiesInstrumentation
Consumables, HPLC, LC columns
IndustriesClinical Research
ManufacturerAgilent Technologies
Key wordsoxidation, mab, bhp, oxidized, methionine, met, hic, residues, mabs, mau, advancebio, oxidant, shallower, monoclonal, antibody, nist, recombinant, variants, chains, separation, time, hydrophobic, protein, stressed, trp, exchanged, side, amino, interaction, slower, reported, species, more, sulfoxide, accessible, reaction, reagents, column, retention, sample, stability, butylhydroperoxide, interleukin, bsabs, hydroperoxide, tert, degradations, kondaveeti, gradient, hplc
Similar PDF
Intact Analysis Using Hydrophobic Interaction - Agilent BioHPLC Columns Application Compendium
2020|Agilent Technologies|Guides
Agilent-NISTmAb Intact Analysis Using Hydrophobic Interaction Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate…
Key words
hic, hicpage, pagehydrophobic, hydrophobicback, backcontents, contentsmab, maboxidized, oxidizedadvancebio, advancebiooxidation, oxidationinteraction, interactionprotein, proteinmonoclonal, monoclonalantibody, antibodymethionine, methioninechemistry
Agilent BioHPLC Columns - Characterization of NIST Monoclonal Antibody Critical Quality Attributes - Application Compendium
2019|Agilent Technologies|Guides
Agilent BioHPLC Columns Characterization of NIST Monoclonal Antibody Critical Quality Attributes Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test…
Key words
mab, mabglycan, glycanadvancebio, advancebiocounts, countsmapping, mappingpeptide, peptidemonoclonal, monoclonalagilent, agilentglycans, glycansmin, mincolumn, columnprotein, proteinmass, massnistmab, nistmabassaymap
Analysis of Monoclonal Antibodies and Antibody-Drug Conjugates Using New Hydrophobic Interaction Chromatography (HIC) Columns
2015|Thermo Fisher Scientific|Posters
150 Absorbance (mAU) including intact mAbs, mAb fragments, engineered variants, and antibody-drug conjugates (ADCs) are being developed for the treatment of cancer and other diseases due to their excellent biocompatibility and high selectivity. The proliferation of monoclonal antibody therapeutics and…
Key words
mab, mabmimic, mimicadc, adcmabpac, mabpacantibody, antibodyhic, hicconjugated, conjugatedabsorbance, absorbancemau, maudrug, drugcys, cysmonoclonal, monoclonaloxidized, oxidizeddar, daraggregates
Quantitation of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS
2011|Agilent Technologies|Applications
Quantitation of Oxidation Sites on a Monoclonal Antibody Using an Agilent 1260 Infinity HPLC-Chip/MS System Coupled to an Accurate-Mass 6520 Q-TOF LC/MS Application Note Authors Abstract Ravindra Gudihal Agilent Technologies India Pvt. Ltd. Bangalore, India The identification of oxidation sites…
Key words
oxidation, oxidationpeptide, peptideoxidized, oxidizedbhp, bhpmet, metmab, mabmethionine, methioninesites, sitestrypsin, trypsinbioconfirm, bioconfirmantibody, antibodywere, weremonoclonal, monoclonalmasshunter, masshunteragilent