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High-Throughput LC/MS Purification of Pharmaceutical Impurities

 

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Application Note Pharma & Biopharma Efficient Purification of Crude Samples in Early-Stage Drug Discovery Using the Agilent 1290 Infinity II Preparative LC/MSD System Authors Sonja Schipperges and Florian Rieck Agilent Technologies, Inc. Abstract In early-stage drug discovery, high-purity compounds are…
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Automated Purification of Compound Libraries Using the Agilent 1260 Infinity Automated LC/MSD Purification System Technical Overview Author Abstract Florian Rieck Purifying a large number of compounds by liquid chromatography usually requires Agilent Technologies, Inc. screening experiments and manual interaction during…
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Technical Overview Developing Purification Strategies for the Agilent 1260 Infinity II Preparative LC/MSD System Author Florian Rieck Agilent Technologies, Inc. Waldbronn, Germany Abstract Peak-based fraction collection triggered by a UV signal threshold leads to satisfactory results in most cases. Some…
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Application Note Pharmaceutical Small Molecules Isolate and Reanalyze Pharma Impurities with the Agilent 1290 Infinity II Autoscale Preparative LC/MSD System API Author Florian Rieck Agilent Technologies, Inc. Abstract Isolation of impurities for further characterization is a routine task in the…
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