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timsTOFMALDI Guided SpatialOMxInnovation with IntegrityTIMS-MALDI MS MALDI Guided SpatialOMxThe tumor microenvironment is ahighly variable ecosystem, giving it anintrinsic temporal character. De-coding thecellular communication within the tumormicroenvironment via label-free MALDIImaging and x-omics promises to improve theunderstanding of the mechanisms responsiblefor drug resistance...
Key words
maldi, malditimstof, timstofspatialomx, spatialomximaging, imagingflex, flexbruker, brukerlaunches, launchesscils, scilstumor, tumorpasef, pasefmicroenvironment, microenvironmentomics, omicstissue, tissuetims, timslab
[ TECHNOLOGY BRIEF ]Metabolic Phenotyping of Colorectal Tissue Samplesby DESI-MSI for Clinical ResearchAnna Mroz,¹ Luisa Doria,¹ Emmanuelle Claude,² and Zoltan Takats¹¹Imperial College, London, UK; ²Waters Corporation, Wilmslow, UKThe examination of lipid profiles and distributionsin healthy and cancerous colorectal tissue samplesmeasured...
Key words
tissue, tissuemsi, msicolorectal, colorectaldesi, desihealthy, healthyimaging, imagingstained, stainedimages, imageshdi, hdilipid, lipidtypes, typesdistribution, distributionbrief, briefcancer, cancercorresponding
Analysis of FFPE treated clinical tissue sections obtained from Human IntraocularMalignancy, Uveal Melanoma by Mass Spectrometry Imaging (MSI)Laura M Cole1, , Hardeep S Mudhar 2, Karen Sisley2, Andrew Peck3, Michael Batey4, Emmanuelle Claude4, Malcolm R Clench1Sheffield Hallam University, Sheffield, UK...
Key words
tumour, tumourcornea, corneanerve, nerveoptic, opticlens, lenseyelid, eyelidmetastases, metastasesintraocular, intraocularspatial, spatialrgb, rgbsections, sectionsimaging, imagingmaldi, maldioverlay, overlayciliary
[ APPLICATION NOTEBOOK ]MS IMAGING AND AMBIENT IONIZATION-MSFOR METABOLOMICS AND LIPIDOMICS1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245ENTABLE OF CONTENTS3 Introduction4 Biomarker Discovery Directly from Tissue Xenograph Using High Definition ImagingMALDI Combined with Multivariate...
Key words
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectiondefinition, definitionmobility, mobilityion, ionhdms, hdmsimage, imagebiomarker, biomarkerspatial, spatialxenograph, xenographdata
 

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timsTOFMALDI Guided SpatialOMxInnovation with IntegrityTIMS-MALDI MS MALDI Guided SpatialOMxThe tumor microenvironment is ahighly variable ecosystem, giving it anintrinsic temporal character. De-coding thecellular communication within the tumormicroenvironment via label-free MALDIImaging and x-omics promises to improve theunderstanding of the mechanisms responsiblefor drug resistance...
Key words
maldi, malditimstof, timstofspatialomx, spatialomximaging, imagingflex, flexbruker, brukerlaunches, launchesscils, scilstumor, tumorpasef, pasefmicroenvironment, microenvironmentomics, omicstissue, tissuetims, timslab
[ TECHNOLOGY BRIEF ]Metabolic Phenotyping of Colorectal Tissue Samplesby DESI-MSI for Clinical ResearchAnna Mroz,¹ Luisa Doria,¹ Emmanuelle Claude,² and Zoltan Takats¹¹Imperial College, London, UK; ²Waters Corporation, Wilmslow, UKThe examination of lipid profiles and distributionsin healthy and cancerous colorectal tissue samplesmeasured...
Key words
tissue, tissuemsi, msicolorectal, colorectaldesi, desihealthy, healthyimaging, imagingstained, stainedimages, imageshdi, hdilipid, lipidtypes, typesdistribution, distributionbrief, briefcancer, cancercorresponding
Analysis of FFPE treated clinical tissue sections obtained from Human IntraocularMalignancy, Uveal Melanoma by Mass Spectrometry Imaging (MSI)Laura M Cole1, , Hardeep S Mudhar 2, Karen Sisley2, Andrew Peck3, Michael Batey4, Emmanuelle Claude4, Malcolm R Clench1Sheffield Hallam University, Sheffield, UK...
Key words
tumour, tumourcornea, corneanerve, nerveoptic, opticlens, lenseyelid, eyelidmetastases, metastasesintraocular, intraocularspatial, spatialrgb, rgbsections, sectionsimaging, imagingmaldi, maldioverlay, overlayciliary
[ APPLICATION NOTEBOOK ]MS IMAGING AND AMBIENT IONIZATION-MSFOR METABOLOMICS AND LIPIDOMICS1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245ENTABLE OF CONTENTS3 Introduction4 Biomarker Discovery Directly from Tissue Xenograph Using High Definition ImagingMALDI Combined with Multivariate...
Key words
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectiondefinition, definitionmobility, mobilityion, ionhdms, hdmsimage, imagebiomarker, biomarkerspatial, spatialxenograph, xenographdata
 

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