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MALDI Mass Spectrometry Imaging RevealsDistinct Spatio-Molecular Phospholipid Distributionsin Mouse LungsWhile phospholipids play key roles in lung physiology and pathology, the complexcomposition and function of the lipidome in the lungs is poorly understood.We applied MALDI mass spectrometry imaging to characterize the...
Key words
imaging, imagingtissue, tissuelungs, lungsimages, imagesmaldi, maldiphospholipids, phospholipidsdistributions, distributionslung, lungwere, werenegative, negativeion, ionscils, scilspositive, positivespatial, spatialbruker
METABOLOMIC/LIPIDOMIC DESI IMAGING OF DIFFERENT CELL CULTURESHadeer Mattar1, Emrys Jones2, Emmanuelle Claude2, Clare Mills11:Division of Infection, Immunity & Respiratory Medicine, Manchester Institute of Biotechnology. University of Manchester, UK; 2: Waters Corporation, Wilmslow, UK.INTRODUCTIONDESI imaging datasets were mined using MassLynx as...
Key words
desi, desiimaging, imagingcell, cellconfluent, confluentwere, werebasophil, basophilbasophilic, basophilicconfluence, confluencerbl, rblcells, cellslipids, lipidsagglomerates, agglomeratesdifferentiators, differentiatorsphotographic, photographicmetaboanalyst
[ TECHNOLOGY BRIEF ]Metabolic Phenotyping of Colorectal Tissue Samplesby DESI-MSI for Clinical ResearchAnna Mroz,¹ Luisa Doria,¹ Emmanuelle Claude,² and Zoltan Takats¹¹Imperial College, London, UK; ²Waters Corporation, Wilmslow, UKThe examination of lipid profiles and distributionsin healthy and cancerous colorectal tissue samplesmeasured...
Key words
tissue, tissuemsi, msicolorectal, colorectaldesi, desihealthy, healthyimaging, imagingstained, stainedimages, imageshdi, hdilipid, lipidtypes, typesdistribution, distributionbrief, briefcorresponding, correspondingcancer
[ APPLICATION NOTEBOOK ]MS IMAGING AND AMBIENT IONIZATION-MSFOR METABOLOMICS AND LIPIDOMICS1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245ENTABLE OF CONTENTS3 Introduction4 Biomarker Discovery Directly from Tissue Xenograph Using High Definition ImagingMALDI Combined with Multivariate...
Key words
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectiondefinition, definitionmobility, mobilityion, ionhdms, hdmsimage, imagebiomarker, biomarkerspatial, spatialxenograph, xenographdata
 

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MALDI Mass Spectrometry Imaging RevealsDistinct Spatio-Molecular Phospholipid Distributionsin Mouse LungsWhile phospholipids play key roles in lung physiology and pathology, the complexcomposition and function of the lipidome in the lungs is poorly understood.We applied MALDI mass spectrometry imaging to characterize the...
Key words
imaging, imagingtissue, tissuelungs, lungsimages, imagesmaldi, maldiphospholipids, phospholipidsdistributions, distributionslung, lungwere, werenegative, negativeion, ionscils, scilspositive, positivespatial, spatialbruker
METABOLOMIC/LIPIDOMIC DESI IMAGING OF DIFFERENT CELL CULTURESHadeer Mattar1, Emrys Jones2, Emmanuelle Claude2, Clare Mills11:Division of Infection, Immunity & Respiratory Medicine, Manchester Institute of Biotechnology. University of Manchester, UK; 2: Waters Corporation, Wilmslow, UK.INTRODUCTIONDESI imaging datasets were mined using MassLynx as...
Key words
desi, desiimaging, imagingcell, cellconfluent, confluentwere, werebasophil, basophilbasophilic, basophilicconfluence, confluencerbl, rblcells, cellslipids, lipidsagglomerates, agglomeratesdifferentiators, differentiatorsphotographic, photographicmetaboanalyst
[ TECHNOLOGY BRIEF ]Metabolic Phenotyping of Colorectal Tissue Samplesby DESI-MSI for Clinical ResearchAnna Mroz,¹ Luisa Doria,¹ Emmanuelle Claude,² and Zoltan Takats¹¹Imperial College, London, UK; ²Waters Corporation, Wilmslow, UKThe examination of lipid profiles and distributionsin healthy and cancerous colorectal tissue samplesmeasured...
Key words
tissue, tissuemsi, msicolorectal, colorectaldesi, desihealthy, healthyimaging, imagingstained, stainedimages, imageshdi, hdilipid, lipidtypes, typesdistribution, distributionbrief, briefcorresponding, correspondingcancer
[ APPLICATION NOTEBOOK ]MS IMAGING AND AMBIENT IONIZATION-MSFOR METABOLOMICS AND LIPIDOMICS1 This notebook is an excerpt from the larger Waters’ Application Notebook on Metabolomics and Lipidomics #720005245ENTABLE OF CONTENTS3 Introduction4 Biomarker Discovery Directly from Tissue Xenograph Using High Definition ImagingMALDI Combined with Multivariate...
Key words
imaging, imagingtissue, tissuemaldi, maldidesi, desihdi, hdisection, sectiondefinition, definitionmobility, mobilityion, ionhdms, hdmsimage, imagebiomarker, biomarkerspatial, spatialxenograph, xenographdata
 

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