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TANDEM ION MOBILITY COUPLED WITH MASS SPECTROMETRY FOR GAS PHASE UNFOLDING STUDIES

 

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INVESTIGATING PRIMARY AND HIGHER-ORDER PROTEIN STRUCTURE ANALYSIS USING A NOVEL CYCLIC ION MOBILITY ENABLED QTOF PLATFORM Scott J. Berger1, Dale A. Cooper-Shepherd2 , Martin Palmer2, LeRoy B Martin1, Henry Shion1, and James I. Langridge2, 1 Waters Corporation, Milford, MA, 01757…
Key words
ims, imscycles, cyclescyclic, cyclictiime, tiimeintensity, intensitypanel, panelmobility, mobilityarrival, arrivalpeptide, peptideenabled, enablednovel, novelunfolding, unfoldingcycle, cycleqtof, qtofprotein
APPLICATION OF CYCLIC ION MOBILITY MASS SPECTROMETRY FOR HIGH PEAK CAPACITY SEPARATIONS OF NATIVE AND DEUTERATED PEPTIDE MIXTURES Martin Palmer1, Dale A. Cooper-Shepherd1, Malcolm Anderson1, James I. Langridge1, Robert Tonge1, John R. Engen2 1 Waters Corporation, Wilmslow, Cheshire, UK, SK9…
Key words
cim, cimsidechain, sidechaincyclic, cyclicdeuteriums, deuteriumsims, imsexchange, exchangeback, backmobility, mobilitydeuteration, deuterationundeuterated, undeuteratedpeptide, peptidedeuterated, deuteratedinfusion, infusionamide, amidepass
USING TRAVELING WAVE ION MOBILITY MASS SPECTROMETRY TO INVESTIGATE NATIVE AND DEUTERATED PROTEINS AND PEPTIDES – NEW CAPABILITIES FOR CORE LABS Roy Martin1, Dale A. Cooper-Shepherd2, 1 Waters Corporation, Beverly MA 01915; 2Waters Corporation, Wilmslow, Cheshire, UK, SK9 4AX OVERVIEW…
Key words
cim, cimsidechain, sidechaindeuteriums, deuteriumsims, imscyclic, cyclicback, backexchange, exchangemobility, mobilitydeuteration, deuterationundeuterated, undeuteratedpass, passdeuterated, deuteratedpasses, passesamide, amidepeptide
A HIGHLY VERSATILE CYCLIC ION MOBILITY – MASS SPECTROMETER FOR ROUTINE TO IN-DEPTH BIOPHARMACEUTICAL CHARACTERIZATION Brad J. Williams1, Margo Wilson2, S. Hunter Walker2, Greg Adams2, Roy Martin1, and Weibin Chen1 1 Waters Corporation, Milford, MA 01757 USA, 2FUJIFILM Diosynth Biotechnologies,…
Key words
ims, imscyclic, cyclicmobility, mobilitymab, mabsubunit, subunitspectrometer, spectrometerbayespray, bayespraybeneficial, beneficialcollision, collisionglycan, glycanbiopharmaceutical, biopharmaceuticalroutine, routinemass, massciu, ciureleased
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