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POSTERT1530-06-41Simplifying workflows for MAM-based critical quality attributemonitoring of biotherapeutics in process development and QCusing a novel LCMS platformScott J Berger, Nilini Ranbaduge, Ying Qing Yu, Min Du, Weibin ChenWaters Corporation, Milford, MACONTACT INFORMATION: Scott_Berger@Waters.comPURPOSE•••Biotherapeutics undergo rigorous characterization and attribute monitoringduring...
Key words
attribute, attributeiyptngyr, iyptngyrpeptide, peptidemam, mammonitoring, monitoringdeamidated, deamidatediyptisodgyr, iyptisodgyrmapping, mappingmodifications, modificationsbased, basedlibrary, libraryfragment, fragmentunifi, unificharacterization, characterizationbiotherapeutics
[ TECHNOLOGY BRIEF ]Routine Peptide Mapping Analysis using the BioAccord SystemNilini Ranbaduge, Henry Shion, and Ying Qing YuWaters Corporation, Milford, MA, USASmartMS-enabled BioAccord System improves theoperational efficiency for routine peptide mapping analysis.GOALDemonstrate how the BioAccord™ Systemsimplifies routine peptide mapping analysiswith...
Key words
bioaccord, bioaccordpeptide, peptidepurposefully, purposefullymapping, mappingsystem, systemaccessibility, accessibilityprotein, proteininformatics, informaticssmartms, smartmsintegrated, integratedbrief, briefflr, flrtuv, tuvacquity, acquityunifi
Application NoteBiotherapeutic Peptide Mass Confirmationand Impurity Profiling on a SmartMSEnabled BioAccord LC-MS SystemKiran Krishnan, Sumit Bobhate, Raghu Tadala, Dr. Padmakar WaghWaters Corporation AbstractThis application note demonstrates how BioAccord LC-MS System can be used for peptide massconfirmation and impurity profiling within research,...
Key words
peptide, peptidebioaccord, bioaccordimpurity, impurityunifi, unifiliraglutide, liraglutidemass, massworkflow, workflowacquity, acquitymapping, mappinguplc, uplcbiotherapeutic, biotherapeuticprofiling, profilingpurity, purityscreening, screeningdisplaying
MONITORING PRODUCT ATTRIBUTES IN BIOPHARMACEUTICALDEVELOPMENT AND QC WITH LC/MSScott J. Berger, Liuxi Chen, Henry Shion, Min Du, Ying Qing YuWaters Corp, Milford, MA, United StatesINTRODUCTIONRESULTS AND DISCUSSION• LC/MS peptide mapping acquisition workflows used forbiotherapeutic characterization can be reapplied to developmentmonitoring...
Key words
unifi, unifiref, refpeptide, peptidemapping, mappingtuv, tuvworkflow, workflowcharacterization, characterizationattributes, attributesreference, referencemse, msemonitoring, monitoringresponse, responselibrary, libraryscreening, screeningnormalized
 

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POSTERT1530-06-41Simplifying workflows for MAM-based critical quality attributemonitoring of biotherapeutics in process development and QCusing a novel LCMS platformScott J Berger, Nilini Ranbaduge, Ying Qing Yu, Min Du, Weibin ChenWaters Corporation, Milford, MACONTACT INFORMATION: Scott_Berger@Waters.comPURPOSE•••Biotherapeutics undergo rigorous characterization and attribute monitoringduring...
Key words
attribute, attributeiyptngyr, iyptngyrpeptide, peptidemam, mammonitoring, monitoringdeamidated, deamidatediyptisodgyr, iyptisodgyrmapping, mappingmodifications, modificationsbased, basedlibrary, libraryfragment, fragmentunifi, unificharacterization, characterizationbiotherapeutics
[ TECHNOLOGY BRIEF ]Routine Peptide Mapping Analysis using the BioAccord SystemNilini Ranbaduge, Henry Shion, and Ying Qing YuWaters Corporation, Milford, MA, USASmartMS-enabled BioAccord System improves theoperational efficiency for routine peptide mapping analysis.GOALDemonstrate how the BioAccord™ Systemsimplifies routine peptide mapping analysiswith...
Key words
bioaccord, bioaccordpeptide, peptidepurposefully, purposefullymapping, mappingsystem, systemaccessibility, accessibilityprotein, proteininformatics, informaticssmartms, smartmsintegrated, integratedbrief, briefflr, flrtuv, tuvacquity, acquityunifi
Application NoteBiotherapeutic Peptide Mass Confirmationand Impurity Profiling on a SmartMSEnabled BioAccord LC-MS SystemKiran Krishnan, Sumit Bobhate, Raghu Tadala, Dr. Padmakar WaghWaters Corporation AbstractThis application note demonstrates how BioAccord LC-MS System can be used for peptide massconfirmation and impurity profiling within research,...
Key words
peptide, peptidebioaccord, bioaccordimpurity, impurityunifi, unifiliraglutide, liraglutidemass, massworkflow, workflowacquity, acquitymapping, mappinguplc, uplcbiotherapeutic, biotherapeuticprofiling, profilingpurity, purityscreening, screeningdisplaying
MONITORING PRODUCT ATTRIBUTES IN BIOPHARMACEUTICALDEVELOPMENT AND QC WITH LC/MSScott J. Berger, Liuxi Chen, Henry Shion, Min Du, Ying Qing YuWaters Corp, Milford, MA, United StatesINTRODUCTIONRESULTS AND DISCUSSION• LC/MS peptide mapping acquisition workflows used forbiotherapeutic characterization can be reapplied to developmentmonitoring...
Key words
unifi, unifiref, refpeptide, peptidemapping, mappingtuv, tuvworkflow, workflowcharacterization, characterizationattributes, attributesreference, referencemse, msemonitoring, monitoringresponse, responselibrary, libraryscreening, screeningnormalized
 

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