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HIGH THROUGHPUT LIPIDOMICS USING ION MOBILITY ENABLED RAPID LC-MS PROFILING SHOWS PROMISE FOR THE ANALYSIS OF HUMAN PLASMA SAMPLES OBTAINED FROM BREAST CANCER PATIENTS

 

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A HIGH THROUGHPUT LC-MS LIPIDOMICS PLATFORM FOR SCREENING & STRATIFYING CANCER SAMPLES FROM BIOBANKS AND CLINICAL TRIALS Adam M King1,2, Robert D Trengove2, Lauren G Mullin3, Bryan Katzenmeyer3, Paul D Rainville3, Giorgis Isaac3, Robert S Plumb3, Lee A Gethings1, and…
Key words
biobanks, biobanksbreast, breastdatabase, databaselipid, lipidcancer, cancerlipids, lipidssearching, searchinglipidomic, lipidomictrials, trialsanalyse, analyseccs, ccsvol, volmin, minpatients, patientsims
[ APPLICATION NOTE ] Rapid Microbore Metabolic Profiling (RAMMP) with Ion Mobility for the Lipidomic Investigation of Plasma from Breast Cancer Patients Adam M. King,1 Lee A. Gethings,1 and Robert S. Plumb 2 1 Waters Corporation, Wilmslow, UK; 2 Waters…
Key words
rammp, rammplipidomic, lipidomicmicrobore, microboremetabolic, metabolicprofiling, profilinglipid, lipidbreast, breastmobility, mobilityinvestigation, investigationpatients, patientscancer, cancerrapid, rapidplasma, plasmauplc, uplccohorts
A RAPID ANALYTICAL PLATFORM FOR BIOFLUID PROFILING IN DISCOVERY METABOLOMICS AND LIPIDOMICS Adam King1,4, Lee Gethings1, Robert Plumb2, Lauren Mullin2, Ian Wilson3, Garth Maker4, Robert Trengove4 1 Waters Corporation, Wilmslow, UK. 2Waters Corporation, Milford, US. 3Imperial College, London, UK. 4Murdoch…
Key words
ims, imsprofiling, profilingmetabolomics, metabolomicslipid, lipidrapid, rapidincrease, increaseccs, ccsphosphotidylserine, phosphotidylserinemobility, mobilityidentificat, identificatrammp, rammphilic, hilicδccs, δccsbiofluid, biofluidgeometrically
[ APPLICATION NOTE ] Biological Interpretation of Breast Cancer Using Rapid Multi-omic Profiling Methods Adam King, Christopher J. Hughes, Giorgis Isaac, Lee A. Gethings, and Robert S. Plumb Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■ ■ ■ Flexible, multi-omic…
Key words
omic, omicbreast, breastcancer, cancerprogenesis, progenesissynapt, synaptprofiling, profilingbiological, biologicalinterpretation, interpretationrapid, rapiddia, diamulti, multiproteomics, proteomicssonar, sonaruplc, uplcacquity
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