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NATIVE MASS SPECTROMETRY DISTINGUISHES HOMO VS HETERO NON-COVALENT DIMERIC AGGREGATES OF MONOCLONAL ANTIBODIES

 

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Agilent Biocolumns Aggregate/Fragment Analysis Application Compendium Contents Background 2 Getting Started 3 How to Guide - Size Exclusion Chromatography for Biomolecule Analysis - 5991-3651EN 4 Featured Application Notes Elevate Your mAb Aggregate Analysis - 5994-2709EN 1 22 22 High-Resolution, High-Throughput…
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AN1611: High-Speed Process Monitoring with UHP-SEC-MALS Sophia Kenrick, Wyatt Technology Corp. Summary Introduction Size exclusion chromatography (SEC) is widely used for detecting aggregates, fragments, and other impurities in a biotherapeutic sample. When coupled with multi-angle light scattering (MALS), SEC enables…
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The Analysis of Multimeric Monoclonal Antibody Aggregates by Size-Exclusion UPLC Stephan Koza, Matthew Lauber, and Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I O N B E N E F I T…
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[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…
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