Robust and Rapid Method for Analysis of Active Pharmaceutical Ingredients in Multi-Component Cold and Flu Medication

 

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STREAMLINED METHOD DEVELOPMENT FOR ACTIVE PHARMACEUTICAL INGREDIENTS IN COLD AND FLU MEDICATION USING A SYSTEMATIC PROTOCOL Authors; Margaret Maziarz(1), Paul Rainville(1) Yukari Haramaki(2) Affiliations (1)Waters Corporation, (2)Waters Asia Pacific INTRODUCTION In this work, we present the development of a MS-compatible…
Key words
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T1230-09-57 Analytical Quality by Design Based Method Development for the Analysis of Cold and Cough Formulations Fadi Alkhateeb , and Paul Rainville, Presenting Author: Fadi Alkhateeb Waters Corporation, Milford, MA [email protected], [email protected] RESULTS The Analytical Target Profile (ATP) is a…
Key words
cough, coughapis, apismethod, methodformulations, formulationsanalytical, analyticalqbd, qbdcold, colddevelopment, developmentboa, boapharmaceutical, pharmaceuticalfusion, fusionguaifenesin, guaifenesinphenylephrine, phenylephrinequality, qualityaqbd
Analytical Quality by Design Based Method Development for the Analysis of Cold and Cough Formulations To create a standard solution with a concentration of 1 μg/mL, phenylephrine, acetaminophen, doxylamine succinate, guaifenesin, dextromethorphan, and diphenhydramine were dissolved in DI water. Chemical…
Key words
cough, coughcold, coldapis, apisguaifenesin, guaifenesinphenylephrine, phenylephrineaqbd, aqbddoxylamine, doxylamineanalytical, analyticalqbd, qbdmethod, methoddextromethorphan, dextromethorphanacetaminophen, acetaminophenfusion, fusionformulations, formulationsexperiment
Application Note Analytical Quality by Design Based Method Development for the Analysis of Cold and Cough Formulations Using an Arc Premier™ System Adam Bengtson, Fadi L. Alkhateeb, Paul D. Rainville Waters Corporation Abstract The separation of active pharmaceutical compounds phenylephrine,…
Key words
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