<p><strong>Metabolomics researchers are often forced to choose between two powerful but different approaches. </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/metabolomics-lipidomics/metabolomics/untargeted-metabolomics.html"><strong>Untargeted metabolomics</strong></a><strong> is great for discovery: it surveys as many metabolites as possible to reveal biology you didn’t know to look for. </strong><a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/metabolomics-lipidomics/metabolomics/targeted-metabolomics.html"><strong>Targeted metabolomics</strong></a><strong> is built for precision: it measures a defined list of metabolites with high sensitivity and quantitative confidence. The challenge is that running both typically costs time, sample, and can introduce variability between workflows.</strong></p><p>In order to deal with this the researchers at Thermo Fisher Scientific have developed <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/content/lifetech/global/en/home/industrial/mass-spectrometry/metabolomics-lipidomics/simultaneous-quantitation-discovery-squad.html"><strong>Simultaneous Quantitation and Discovery (SQUAD)</strong></a> analysis as shown in this technical note <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004327_ov_squad_metabolomics_orbitrap_astral_tn004327_na_en_290c75edd9.pdf"><strong>Simultaneous Quantitation and Discovery Analysis: Combining Targeted and Untargeted Metabolomics on Orbitrap Mass Spectrometers</strong></a>,<strong> </strong>a hybrid strategy that combines targeted quantitation and untargeted discovery in a single experiment. In practice, SQUAD lets you quantify a predefined metabolite panel using calibration curves built from authentic standards and isotopically labeled internal standards, while still capturing rich full-scan data that supports retrospective mining and identification of unknowns.</p><p>A key theme of the technical note is that results are only as strong as the experiment design and quality controls. The workflow emphasizes calibration strategy, careful extraction choices (aligned to metabolite classes), and the smart use of blanks, pooled QCs, and system suitability tests to monitor drift, contamination, and reproducibility across a batch.</p><p>SQUAD is also designed to scale across different Thermo Scientific Orbitrap mass spectrometers. The technical note outlines how the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1491"><strong>Thermo Scientific Orbitrap Exploris mass spectrometers</strong></a><strong> </strong>can use MS1-based SQUAD with polarity switching and optionally add tSIM/tMS2 for targeted sensitivity, while the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=Tribrid"><strong>Thermo Scientific Orbitrap Tribrid mass spectrometers</strong></a> can pair high-resolution MS1 discovery with rapid ion-trap tMS2 quantitation, boosted by tools like <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1763"><strong>Thermo Scientific AcquireX Intelligent Data Acquisition</strong></a><strong> </strong>and Real-Time Library Search (RTLS).</p><p>Finally, the data story comes together in software: <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/77"><strong>Thermo Scientific TraceFinder Software</strong></a> for targeted quantitation and <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1759"><strong>Thermo Scientific Compound Discoverer Software </strong></a>for untargeted discovery, annotation, and statistics, turning one injection into both confident numbers and new biological leads.</p><blockquote><div><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/labrulez-bucket-strapi-h3hsga3/tn_004327_ov_squad_metabolomics_orbitrap_astral_tn004327_na_en_290c75edd9.pdf"><span><strong>Download the SQUAD technical note</strong></span></a></div></blockquote><p><strong>Visit us on&nbsp;</strong><a target="_blank" rel="noopener noreferrer" href="https://www.linkedin.com/showcase/72003132/admin/dashboard/"><strong><u>LinkedIn:</u></strong></a><strong>&nbsp;</strong>#SQUAD #Metabolomics #Lipidomics</p>

One Injection, Two Answers: Introducing Squad Metabolomics on Orbitrap Mass Spectrometers

<h3><a target="_blank" rel="noopener noreferrer" href="https://www.isc2026.org/"><strong>ISC 2026</strong></a></h3><p><strong>The </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/companies/314"><strong>International Symposium on Chromatography (ISC)</strong></a><strong> represents the oldest conference series on separation science. ISC symposia have been organised since 1956 in each even year. ISC is one of the premier meetings series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.</strong></p><h4><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/events/644"><strong>35th International Symposium on Chromatography</strong></a></h4><p>📆<strong>6. - 10. September 2026</strong></p><p>📍<strong>Prague, Czech Republic</strong></p><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://www.czech-in.org/cmPortalV15/Account/Login?ReturnUrl=%2FcmPortalV15%2FPortal%2FISC26%2Fnormal"><strong>Register HERE for the ISC 2026</strong></a></p><p><strong>Late Registration until 25 August 2026!</strong></p><p><strong>From 26 August 2026 only Onsite Registration.</strong></p></blockquote><h4><strong>Publishing Workshop</strong></h4><ul><li>Wednesday, 9 September 2026&nbsp;</li><li>12:30–14:00&nbsp;</li></ul><p>This interactive workshop will provide practical guidance on scientific publishing in the field of separation science. Participants will have the opportunity to hear directly from journal editors about key aspects of the publication process and how to improve their chances of successful publication.</p><p>Topics will include <strong>manuscript preparation, peer review</strong>, <strong>editorial decision-making, open access publishing</strong>, and the responsible <strong>use of artificial intelligence in scientific publishing</strong>. Editors will share insights into what they look for in submissions, common reasons for rejection, and strategies for preparing strong manuscripts. The workshop will also cover selected Wiley-specific topics, including the publisher’s submission platform and current guidelines on the use of AI in scientific publications.</p><p>The session will include opportunities for questions and discussion, allowing participants to interact directly with editors and gain valuable advice for their future publishing activities.</p><h5><strong>Attending Editors-in-Chief:</strong></h5><ul><li><strong>Michael Lämmerhofer</strong> — Journal of Separation Science and Separation Science Plus&nbsp;</li><li><strong>Sebastiaan Eeltink</strong> — Analytical Science Advances&nbsp;</li><li><strong>Mario Thevis</strong> — Drug Testing &amp; Analysis&nbsp;</li></ul>

Publishing Workshop at ISC 2026

<p><strong>We are excited to announce that the 18th MDCW will take place from January 25-27, 2027, in Liège, Belgium. This in-person event will feature:</strong></p><ul><li><strong>Keynote presentations</strong> from leading researchers</li><li><strong>Flash talks and poster sessions</strong> highlighting the latest innovations</li><li><strong>Focus group discussions</strong> addressing current challenges and future developments</li><li>💸<strong>FREE registration </strong>ensures that this event remains accessible to all researchers, students, and industry professionals interested in multidimensional chromatography. ​​We hope to see you there!</li></ul><h3><strong>Registration</strong></h3><blockquote><p class="cke-user_style-important"><strong>👉</strong><a target="_blank" rel="noopener noreferrer" href="https://app.oxfordabstracts.com/auth?redirect=https%3A%2F%2Fapp.oxfordabstracts.com%2Fregister%2Fevent%2F77272%3Fpreview%3Dfalse"><strong>Register HERE</strong></a></p><p><strong>Registration deadline: December 1, 2026</strong></p></blockquote><h3><strong>Abstract Submission</strong></h3><p>Abstracts for <strong>oral presentations</strong> must be submitted by <strong>September 15, 2026</strong>, to be considered.</p><p><strong>​Poster abstracts</strong> submitted by <strong>September 15, 2026</strong>, will be included in the <strong>preliminary program</strong>. Additional <strong>last-minute poster submissions </strong>will be accepted until <strong>November 30, 2026</strong>, for inclusion in the final program.</p><blockquote><p class="cke-user_style-important">👉<a target="_blank" rel="noopener noreferrer" href="https://app.oxfordabstracts.com/auth?redirect=/stages/81780/submitter"><strong>Submit your abstract HERE</strong></a></p><p><strong>&nbsp;Deadline for abstract submission: September 15, 2026</strong></p></blockquote><h4><strong>Presentation guidelines</strong></h4><h5><strong>Poster Presentations</strong></h5><ul><li><strong>Presenters must print and bring their own posters</strong>—onsite printing services and mailed submissions are not available.</li><li>Posters should be in <strong>landscape format: 36" tall × 48" wide</strong>.</li><li>Set up your poster <strong>during registration</strong> on the day of your assigned session and remove it at the <strong>end of the same day</strong>.</li><li>Poster presenters <strong>must</strong> be present at their posters during the designated poster session.</li><li>Posters will also be available for viewing <strong>during coffee and lunch breaks</strong>.</li><li>Presenters may optionally stand by their posters during these times for further discussions.</li></ul><h5><strong>Oral Presentations</strong></h5><ul><li><strong>Keynote presentations: </strong>30 minutes (25–28 min + Q&amp;A)</li><li><strong>Full oral presentations: </strong>20 minutes (18 min + 2 min Q&amp;A)</li><li><strong>Flash presentations: </strong>10 minutes (8 min + 2 min Q&amp;A)</li></ul><p><strong>Presentation Format:</strong></p><ul><li>Submit your slides as a <strong>PowerPoint (PPT)</strong> file (.ppt or .pptx).</li><li>Name your file with program code and surname, e.g. "O-28 Smith.pptx".</li><li>For optimal display, use <strong>16:9 slide format </strong>(4:3 is also supported).</li></ul><p><strong>Technical &amp; Session Logistics:</strong></p><ul><li>A <strong>headset or portable microphone</strong> will be available.</li><li>A <strong>laser pointer with a slide change button</strong> will be provided.</li><li>Ensure your presentation allows time for <strong>questions</strong> within your allocated time.</li><li><strong>Before your session</strong>, check in and introduce yourself to the conference or session chairs.</li></ul><h3><strong>Program</strong></h3><h4><strong>Keynote Speakers</strong></h4><h5><strong>Finding Clarity in Challenging Samples: Multiple Heart-Cutting 2D-LC and the Technologies That Enable It &nbsp; &nbsp;</strong></h5><ul><li>Stephan Buckenmaier (Principal Scientist R&amp;D, Agilent Technologies)</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/MDCW_Stephan_Buckenmaier_c84239ec30.jpg" alt="MDCW: Stephan Buckenmaier" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_MDCW_Stephan_Buckenmaier_c84239ec30.jpg 151w," sizes="100vw" width="284" height="294"></p><p>Stephan Buckenmaier is a Principal Scientist in R&amp;D at Agilent Technologies, specializing in advanced separation science and the development of two-dimensional liquid chromatography (2D-LC) solutions. Since joining Agilent in 2006, he has held a variety of scientific and technical roles, with a particular focus on innovative chromatographic technologies. He earned his Ph.D. from the University of the West of England (Bristol, UK) and conducted postdoctoral research at the University of Tübingen. Stephan has authored numerous scientific publications, contributed a book chapter, and is listed as an inventor on numerous patents in the field of separation science. He regularly presents his work at international scientific conferences.</p><h4><strong>Short Course</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/18th_MDCW_short_course_41ecd3c6cf.jpg" alt="18th MDCW: Short course" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_18th_MDCW_short_course_41ecd3c6cf.jpg 245w," sizes="100vw" width="1100" height="619"></p><p>There will be <strong>20 spaces available</strong> in a short course related to multidimensional chromatography. If you want to register for the short course, indicate so during your registration. We will send a separate link to pay for the short course to reserve your seat (<strong>$50 USD</strong>).&nbsp;</p><h4><strong>A Beginner’s Guide to Multidimensional Chromatography short course</strong></h4><ul><li><strong>Instructors:</strong> Pierre-Hugues Stefanuto, Katelynn Perrault Uptmor, Dwight Stoll, Petr Vozka</li></ul><h5><strong>Course Description&nbsp;</strong></h5><p>So...you want to do multidimensional chromatography? If you are getting started in the field using either liquid or gas chromatography, you’re in the right place. This course will cover a brief history and introduction to both multidimensional gas chromatography and multidimensional liquid chromatography. Discussion will also include basic system components and data handling strategies to apply after acquiring your data. A hands-on portion of the course will also include familiarization with common system components and consumables for both GC and LC, as well as the opportunity to use a commercial GC×GC instrument.</p><h5><strong>Target Participants&nbsp;</strong></h5><p>This course is intended to be an initial touchpoint for those who are looking to explore multidimensional chromatography as a new option/capability, or who might be using it for the first time. The course is intended for new users to obtain a background on the techniques as a primer to the workshop. &nbsp;Advanced topics will not be discussed.</p><h5><strong>Course Logistics&nbsp;</strong></h5><ul><li>Morning Session (8:30 AM – 12:00 PM)</li><li>Afternoon Session (1:00 PM – 4:30 PM)</li></ul><p><strong>Lunch and coffee will be provided.</strong></p><h5><strong>Cost&nbsp;</strong></h5><p>A <strong>$50 fee</strong> is required to reserve a spot in the course. <strong>20 seats are available</strong>. An expression of interest form will be available to indicate interest in a seat within the course. On November 10th, participants will be informed about seat availability and the payment process will be communicated.</p><h4><strong>Outline (Total Time ~ 4 hrs)&nbsp;</strong></h4><h5><strong>Part I (1 hr) – History, Terminology, Fundamental Concepts&nbsp;</strong></h5><ul><li>Brief history of the development of multidimensional separations&nbsp;</li><li>Terminology&nbsp;</li><li>Fundamental Concepts&nbsp;<ul><li>In what ways are multidimensional separations useful for analytical chemistry / measurement science?&nbsp;</li><li>First and second separations should be orthogonal / complementary&nbsp;</li><li>Fast second dimension separations are important to avoid undersampling&nbsp;</li><li>Structured chromatograms can provide chemical insight and facilitate data interpretation&nbsp;</li><li>Highlights of an example data processing workflow – from raw data to actionable information &nbsp;</li></ul></li><li>Break (30 min)&nbsp;</li></ul><h5><strong>Part II (1.5 hrs) Introduction to Multidimensional Gas Chromatography&nbsp;</strong></h5><ul><li>Method basics&nbsp;<ul><li>Column selection&nbsp;</li><li>Method parameters&nbsp;</li><li>Carrier gas choices&nbsp;</li><li>Detector considerations&nbsp;</li></ul></li><li>Modulator selection with a focus on current market options&nbsp;<ul><li>Thermal modulators&nbsp;</li><li>Flow modulators&nbsp;</li><li>Other commercial options&nbsp;</li></ul></li><li>Method development made simple&nbsp;</li><li>Data preprocessing and initial handling&nbsp;</li><li>Lunch (1 hr)&nbsp;</li></ul><h5><strong>Part III (1 hr) Introduction to Multidimensional Liquid Chromatography&nbsp;</strong></h5><ul><li>Modes of multidimensional separation commonly used with LC&nbsp;<ul><li>Heartcut&nbsp;</li><li>Multiple heartcut / selective comprehensive&nbsp;</li><li>Fully comprehensive&nbsp;</li></ul></li><li>Interfaces used for multidimensional LC (i.e., the hardware that does the transfer from first to second dimension)&nbsp;</li><li>Common use cases of multidimensional LC illustrated using examples from industry and academic research&nbsp;<ul><li>Evaluating peak purity&nbsp;</li><li>Unknown identification via multidimensional and MS or NMR detection&nbsp;</li><li>Multi-stage separation with analyte transformation between stages&nbsp;</li><li>Multi-attribute methods&nbsp;</li><li>Making complete analysis of moderately complex samples attainable in a reasonable analysis time&nbsp;</li><li>Digging deeper – comprehensive separations for comprehensive analysis&nbsp;<br>Introduction to method development strategies&nbsp;</li></ul></li></ul><h5><strong>Part IV (2 hrs) Laboratory Instrument Familiarization</strong></h5><h5><strong>Part V (30 min) Wrap-up and Q&amp;A &nbsp;</strong></h5><h4><strong>Venue</strong></h4><ul><li>University of Liege</li><li>Pl. du Vingt Août 7</li><li>4000 Liège</li><li>​Belgium</li><li><strong>​Main Room:</strong> Salle Academique</li></ul>

18th MDCW - Registration and abstract submission opens

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Thermo Fisher Scientific

The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

Thermo Scientific Stellar Mass Spectrometer

Move biomarker candidates from discovery to validation more efficiently, confidently, and at lower cost with breakthroughs in extended scale, massive throughput, higher sensitivity, greater specificity, and unrivaled productivity.

<div><div id="container-a1c36dfacf"><div><div><div id="text-913638046"><p><strong>A new paradigm for targeted quantitation.&nbsp;Move biomarker candidates from discovery to validation more efficiently, confidently, and at lower cost with breakthroughs in extended scale, massive throughput, higher sensitivity, greater specificity, and unrivaled productivity.</strong></p><p>The Thermo Scientific Stellar Mass Spectrometer introduces revolutionary technology combining robust quantitation with the specificity of rapid full scan MS<sup>n</sup>&nbsp;acquisition creating unrivaled improvements in laboratory productivity.</p><div><div id="text-801893275"><h3><strong>Expanded experimental capabilities to meet the most challenging biomarker verification</strong></h3></div></div><div><div id="container-1e8e478f3a"><div><div><div id="text-1204752335"><p>The Thermo Scientific Stellar Mass Spectrometer offers an array of data acquisition capabilities to deliver robust and reproducible quantitation for a wide range of analytes across an extended dynamic range.</p></div></div></div></div></div><h4><strong>System highlights</strong></h4><div><div id="container-a89a56f063"><div><div><div id="text-451891225"><h5><strong>Improve ionization efficiency for more compounds at higher LC flow rates&nbsp;</strong></h5></div></div><div><div id="text-1671602085"><p>For a wider range of compounds separated using liquid chromatography operated at analytical flow rates, the Stellar Mass Spectrometer comes equipped with the Thermo Scientific OptaMax Plus Ion Source, which can deliver higher vaporizer temperatures to improve desolvation and ionization potentials.</p></div></div></div></div></div><figure class="image"><img style="aspect-ratio:1290/725;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Stellar_revolucni_hmotnostni_spektrometr_SF_Sys_Opta_Max_c303cf500a.jpg" alt="Thermo Fisher Scientific: Thermo Scientific Stellar Mass Spectrometer - SF Sys OptaMax" width="1290" height="725"></figure><div><div id="container-d79c3b2946"><div><div><div id="text-251514658"><h5><strong>Spend less time on instrument set-up and focus on the science</strong></h5></div></div><div><div id="text-989104128"><p>Trigger on-demand or scheduled system calibrations remotely and without disruption to your LC-MS system with the integrated Auto-Ready ion source.</p></div></div></div></div></div><div><div id="container-81dd07c9bb"><div><div><div id="text-1289282711"><h5><strong>Improve ion utilization by extending the capabilities of the new collision cell</strong></h5></div></div><div><div id="text-1641484825"><p>The ion concentrating routing multipole (ICRM) is a curved collision cell performing both beam-type fragmentation (HCD) and precursor/product ion accumulation capabilities as controlled by dynamic automatic gain control (AGC) with synchronized ion packet release to the high-pressure linear ion trap for downstream manipulation or detection.</p></div></div></div></div></div><figure class="image"><img style="aspect-ratio:1290/725;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Stellar_revolucni_hmotnostni_spektrometr_SF_Sys_ICRM_3b2326f3af.jpg" alt="Thermo Fisher Scientific: Thermo Scientific Stellar Mass Spectrometer - SF Sys ICRM" width="1290" height="725"></figure><div><div id="container-dbf5a6cdd9"><div><div><div id="text-813962034"><h5><strong>Efficiently manage ion populations for fast and sensitive analysis</strong></h5></div></div><div><div id="text-2033771024"><p>The&nbsp;hyper-fast dual-pressure linear ion trap mass analyzer expands analytical capabilities while maximizing fast, high-quality data acquisition.</p><p>The differential neutral pressures maintained in the high- and low-pressure linear ion traps prepares ions for higher-order manipulation or fast and sensitive ion ejection at scan rates up to 220 kDa/S, but typically operates at 125 kDa/S for robust data acquisition.</p></div></div></div></div></div><div><div id="container-9a523f34e0"><div><div><div id="text-1491120095"><h5><strong>Extended analytical capabilities to increase laboratory productivity</strong></h5></div></div><div><div id="text-328051555"><p>The high-pressure linear ion trap maximizes ion packet manipulation enabling multi-notch RF excitation for dissociation or ejection for SIM, higher order MS<sup>n</sup>, SPS MS<sup>3</sup>, or data-independent acquisition (DIA) to address the most challenging quantitative experiments.&nbsp;</p><div><div id="container-82e5907416"><div><div><div id="text-693866740"><h5><strong>Leverage single ion detection sensitivity to address the most challenging quantitation demands</strong></h5></div></div><div><div id="text-737565098"><p>Efficient and sensitive ion detection drives improved quantitative performance at scale. The dual conversion dynode configuration coupled to the photomultiplier tube detects ca. 84% of trapped ions for single ion sensitivity.</p></div></div></div></div></div></div></div></div></div></div><figure class="image"><img style="aspect-ratio:2048/1152;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Stellar_hmotnostni_spektrometr_SF_Sys_Extended_Scale_750dc20128.jpg" alt="Thermo Fisher Scientific: Thermo Scientific Stellar Mass Spectrometer - SF Sys Extended Scale" width="2048" height="1152"></figure><div><div id="text-1993749933"><h5><strong>Automated intelligence manages tMSn acquisition</strong></h5></div></div><div><div id="text-1206797739"><p>Streamline tMSn method creation and data acquisition management. PRM Conductor software effectively and efficiently creates robust targeted quantitative methods and manages reproducible data acquisition and processing.</p></div></div><div><div id="container-b03b606507"><div><div><div id="text-2005266584"><h5><strong>Maximize data completeness with the Adaptive RT routine</strong></h5></div></div><div><div id="text-671832198"><p>Eliminate the cost and time of optimizing RT kits to the study samples to boost timed/scheduled data acquisition performance using the Adaptive RT routine.</p><p>The method leverages a novel real-time mapping routine to dynamically adjust timed/scheduled data acquisition windows at narrower time intervals to eliminate missing values that compromise data quality.&nbsp;</p></div></div></div></div></div><figure class="image"><img style="aspect-ratio:1290/654;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Thermo_Scientific_Stellar_revolucni_hmotnostni_spektrometr_SF_Sys_PRM_Conductor_5b596e7e4c.jpg" alt="Thermo Fisher Scientific: Thermo Scientific Stellar Mass Spectrometer - SF Sys PRM Conductor" width="1290" height="654"></figure><div><div id="container-a192ba4b83"><div><div><div id="container-38d4c699d2"><div><div><div id="text-1578189934"><h5><strong>Industry-leading polarity switching speeds increase laboratory productivity</strong></h5></div></div><div><div id="text-1173595596"><p>Reduce the time, cost, and challenges associated with creating and implementing highly multiplexed quantitative metabolite analysis. Fast polarity switching speeds enable comprehensive compound interrogation in +ESI and -ESI at all MS<sup>n</sup> levels on an LC timescale.</p><div><div id="container-b5fb525888"><div><div><div id="text-18006314"><h5><strong>Environmentally friendly dry pumps decrease energy usage and maintenance</strong></h5></div></div><div><div id="text-1704557304"><p>Changing from two oil-based fore pumps to a single dry pump reduces heat output by 22% and decreases maintenance.</p><p>The use of a single dry pump also eliminates oil vapors and the need for oil checks and changes.</p><h3><strong>Solutions for additional research support</strong></h3><div><h4><strong>Translational proteomics</strong></h4><p>The Stellar Mass Spectrometer offers new possibilities for translational proteomics with improved specificity for greater quantitative performance at scale.</p><h4><strong>Quantitative proteomics</strong></h4><p>Accurate and precise quantitation for label-free and TMT multiplexing sample analysis strategies with the Stellar Mass Spectrometer.</p><div><h4><strong>Metabolomics and Lipidomics</strong></h4><p>Extended analytical capabilities quantify more metabolites and lipids with greater specificity using faster liquid chromatography gradients to increase laboratory productivity.</p></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div></div>

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One Injection, Two Answers: Introducing Squad Metabolomics on Orbitrap Mass Spectrometers

18th MDCW - Registration and abstract submission opens

Publishing Workshop at ISC 2026